Methods for gauging the effect of a depression treatment by...

Details Methods for gauging the effect of a depression treatment by... Methods for gauging the effect of a depression treatment by...

2005-08-03

2010-06-15

Saoud, Christine J (Department: 1649)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Testing efficacy or toxicity of a compound or composition

C436S514000, C436S516000, C436S518000, C424S009100

Reexamination Certificate

active

07736621

ABSTRACT:
The invention provides a diagnostic composition for detecting an affective disorder comprising an antibody selected from the group consisting of an antibody to a beta-arrestin, an antibody to a G-protein coupled receptor kinase and combinations thereof as the active detecting agent therein.

REFERENCES:
Nestler et al. Neuron. 2002 34: 13-25.
Grange-Midroit et al. Mol Brain Res. 2003, 111: 31-41.
Avissar et al. Am. J. Psychiatry. Nov. 2004. 161: 2066-2072.
Avissar et al. Am. J. Psychiatry. 1997. 154: 211-217.
Bohn et al., NeuroMolecular Medicine. 2004. 5:41-50.
“Towards Molecular Diagnostics of Mood Disorders In Psychiatry,”Trends in Molecular Medicine, 8: 294-300, by Sofia Avissar et al., 2002.
“Applications of G Proteins in the Molecular Diagnosis of Psychiatric Disorders,”Expert Review of Molecular Diagnosis, 3: 89-100, by Sofia Avissar et al., 2003.

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