Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide
Reexamination Certificate
2006-09-19
2006-09-19
Gambel, Phillip (Department: 1644)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using tissue cell culture to make a protein or polypeptide
C435S070100, C435S070200, C435S070300, C435S007100, C800S006000, C530S388150, C530S388100, C530S388200, C530S388220, C530S388700, C530S388750
Reexamination Certificate
active
07109003
ABSTRACT:
In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucelotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein.
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Corvalan Jose Ramon
Davis C. Geoffrey
Gilman Steven Christopher
Hanke Jeffrey Herbert
Hanson Douglas Charles
Abgenix, Inc.
Fish & Neave IP Group Ropes & Gray LLP
Gambel Phillip
Gunnison, Esq. Jane T.
Haley, Jr., Esq. James F.
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