Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2002-02-01
2008-12-09
Sisson, Bradley L (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S006120, C435S091200, C435S183000, C536S023100, C536S024310, C536S024330, C530S350000
Reexamination Certificate
active
07462447
ABSTRACT:
The invention provides mutant SH3-binding protein (SH3BP2) nucleic acids, polypeptides, and agents which selectively bind to the mutant SH3BP2 molecules and which do not bind to the wild type SH3BP2 molecules. Methods for selecting agents which inhibit mutant SH3BP2 expression, as well as diagnostic and therapeutic methods which utilize the mutant SH3BP2 molecules for diagnosing and treating disorders of bone homeostasis, also are provided.
REFERENCES:
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Olsen Bjorn R.
Reichenberger Ernst
Tiziani Valdenize
Ueki Yasuyoshi
President and Fellows of Harvard College
Sisson Bradley L
Wolf Greenfield & Sacks P.C.
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