Methods for enhancing permeation of a topically administered phy

Details Methods for enhancing permeation of a topically administered phy Methods for enhancing permeation of a topically administered phy

1996-04-26

2000-01-04

Bawa, Raj

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

424 46, 424433, 424DIG15, 424 43, 514937, 514944, 514936, 514947, 514946, A61K 906

Patent

active

060106913

ABSTRACT:
The permeation of a therapeutic agent through the epithelium by topical administration is enhanced by the further topical administration of a stearylamine, transvaccenic acid or a combination of a stearylamine and transvaccenic acid.

REFERENCES:
patent: 4177267 (1979-12-01), Herschler
patent: 5015470 (1991-05-01), Gibson
patent: 5073372 (1991-12-01), Turner et al.
patent: 5215759 (1993-06-01), Mausner
patent: 5482965 (1996-01-01), Rajadhyaksha
Tsai, J.C et al. (1996). J. Pharmaceutical Sci 85(6):643-648.

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