Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-10-17
2006-10-17
Monshipouri, Maryam (Department: 1653)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S252300, C435S320100
Reexamination Certificate
active
07122350
ABSTRACT:
The present invention provides two novelE. colisynthetic promoters, Syn 1 and Syn 2. Syn 1 and Syn 2 are two tight regulated synthetic promoters that control uninduced, leaky expression of proteins that are toxic and interfere with production of recombinant protein from anE. coliexpression system.
REFERENCES:
patent: 5545541 (1996-08-01), Molin et al.
patent: 6271359 (2001-08-01), Norris et al.
Estrem et al., “Identification of an UP element consensus sequnece for bacterial promoters,” Proc. Natl. Acad. Sci. USA (Aug. 18, 1998), 95(17), p. 9761-6.
Chan Chung
Pownder Tracey A.
Monshipouri Maryam
Rooke Agnes
Walker Shelby J.
ZymoGenetics Inc.
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