Methods for enhancing differentiation and proliferation of hemat

Details Methods for enhancing differentiation and proliferation of hemat Methods for enhancing differentiation and proliferation of hemat

1985-06-24

1989-03-14

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

A61K 3166

Patent

active

048124435

ABSTRACT:
A medicament containing a compound of the formula ##STR1## wherein ##STR2## is a trans-isoprene unit, ##STR3## is a cis-isoprene unit, and n is an integer of from 12 to 18, or a pharmaceutically acceptable ester thereof.
The medicament is useful for the treatment of anemia, particularly aplastic anemia.

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Kennan et al., Biochem. Journal, vol. 165, pp. 405-408 (1977).
Carson et al., Proc. Natl. Acad. Sci. U.S.A., vol. 76, pp. 5709-5713 (1979).
Carson et al., J. Biological Chemistry, vol. 256, pp. 4679-4686 (1981).
Potter et al., Biochem. Biophys. Res. Comm., vol. 106, pp. 691-696 (1982).
Potter et al., Journal of Biological Chemistry, vol. 256, pp. 2371-2376 (1981).

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