Methods for embolizing aneurysmal sites with a high...

Surgery – Instruments – Internal pressure applicator

Reexamination Certificate

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Reexamination Certificate

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10345127

ABSTRACT:
Novel methods for embolizing blood vessels which are particularly suited for treating aneurysms are provided. The presently disclosed methods provide for the embolization of aneurysms wherein occlusion of the neck of the aneurysm during embolization by a flow arresting device such as balloon is not required. In one embodiment, the compositions employed in the methods of this invention comprise a biocompatible polymer, a biocompatible solvent and a biocompatible contrast agent wherein the viscosity of this composition is at least about 1000 centistokes at 40° C. and, preferably, at least about 2500 centistokes at 40° C.

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“Detachable Coil Embolization” downloaded from the world wide web on Feb. 26, 2007.
“Aneurysm Embolization” downloaded from the world wide web on Feb. 26, 2007.
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Kinugasa, M.D., Kazushi et al., “Direct thrombosis of aneurysms with cellulose polymer,” 77 J. Neurosurg pp. 501-507 (1992).
Kinugasa, M.D., Kzaushi et al. “Early treatment of subarachnoid hemmorrhage after preventing rerupture of an aneurysm,” 83 J. Neurosurg. pp. 34-41 (1995).
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Mandai, Shinya et al., “Direct thrombosis of aneurysms with cellulose acetate polymer,” 77 J. Neurosurg. pp. 497-500 (1992).
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