Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2007-03-27
2009-06-30
Benzion, Gary (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
C435S071100, C424S009100, C424S009200, C436S518000, C436S528000
Reexamination Certificate
active
07553616
ABSTRACT:
The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.
REFERENCES:
patent: 4511659 (1985-04-01), Matson
patent: 4863873 (1989-09-01), Matson
patent: 5104639 (1992-04-01), Matson
patent: 5541310 (1996-07-01), Ward et al.
patent: 5565323 (1996-10-01), Parker et al.
patent: 5824467 (1998-10-01), Mascarenhas
patent: 5871712 (1999-02-01), Siman
patent: 5880146 (1999-03-01), Gillies et al.
patent: 5977083 (1999-11-01), Burcoglu
patent: 6004755 (1999-12-01), Wang
patent: 6053866 (2000-04-01), McLeod
patent: 6087090 (2000-07-01), Mascarenhas
patent: 6168933 (2001-01-01), Kaser et al.
patent: 6190858 (2001-02-01), Persaud et al.
patent: 6194217 (2001-02-01), Matson
patent: 6210970 (2001-04-01), Matson
patent: 6218117 (2001-04-01), Herrnstadt et al.
patent: 6258605 (2001-07-01), Chace
patent: 6287790 (2001-09-01), Lelievre et al.
patent: 6303365 (2001-10-01), Martin et al.
patent: 6319668 (2001-11-01), Nova
patent: 6326163 (2001-12-01), Forssmann et al.
patent: 6326164 (2001-12-01), Rice et al.
patent: 6344322 (2002-02-01), Polyak et al.
patent: 6350588 (2002-02-01), Roth et al.
patent: 6376210 (2002-04-01), Yuan
patent: 6558955 (2003-05-01), Kristal et al.
patent: 6677160 (2004-01-01), Stockman et al.
patent: 6680203 (2004-01-01), Dasseux et al.
patent: 7005255 (2006-02-01), Kaddurah-Daouk et al.
patent: 7329489 (2008-02-01), Kaddurah-Daouk et al.
patent: 2002/0009740 (2002-01-01), Kaddurah-Daouk et al.
patent: 2002/0081626 (2002-06-01), Kaddurah-Daouk et al.
patent: 2003/0229451 (2003-12-01), Hamilton et al.
patent: 2004/0002842 (2004-01-01), Woessner et al.
patent: 2004/0018500 (2004-01-01), Glassbrook et al.
patent: 2004/0018501 (2004-01-01), Allen et al.
patent: 2004/0019429 (2004-01-01), Coffin et al.
patent: 2004/0019430 (2004-01-01), Hurban et al.
patent: 2004/0019435 (2004-01-01), Winfield et al.
patent: 2004/0023295 (2004-02-01), Hamilton et al.
patent: 2004/0024293 (2004-02-01), Lawrence et al.
patent: 2004/0024543 (2004-02-01), Zhang et al.
patent: 2006/0134676 (2006-06-01), Kaddurah-Daouk et al.
patent: 2006/0134677 (2006-06-01), Kaddurah-Daouk et al.
patent: 2006/0134678 (2006-06-01), Kaddurah-Daouk et al.
patent: 2007/0026389 (2007-02-01), Kaddurah-Daouk et al.
patent: 2007/0072203 (2007-03-01), Kaddurah-Daouk et al.
patent: 2007/0172820 (2007-07-01), Kaddurah-Daouk et al.
patent: 2007/0172885 (2007-07-01), Kaddurah-Daouk et al.
patent: WO-86/03006 (1986-05-01), None
patent: WO-92/13273 (1992-08-01), None
patent: WO-93/10802 (1993-06-01), None
patent: WO-96/23075 (1996-08-01), None
patent: WO-98/29563 (1998-07-01), None
patent: WO-98/37423 (1998-08-01), None
patent: WO-99/27361 (1999-06-01), None
patent: WO-99/37786 (1999-07-01), None
patent: WO-99/37786 (1999-07-01), None
patent: WO-99/38013 (1999-07-01), None
patent: WO-99/44062 (1999-09-01), None
patent: WO-99/50437 (1999-10-01), None
patent: WO-00/07025 (2000-02-01), None
patent: WO-00/07025 (2000-02-01), None
patent: WO-00/09759 (2000-02-01), None
patent: WO-00/51054 (2000-08-01), None
patent: WO-00/55346 (2000-09-01), None
patent: WO-00/55346 (2000-09-01), None
patent: WO-00/65039 (2000-11-01), None
patent: WO-00/65039 (2000-11-01), None
patent: WO-00/65472 (2000-11-01), None
patent: WO-01/00819 (2001-01-01), None
patent: WO-02/04957 (2001-01-01), None
patent: WO-01/09341 (2001-02-01), None
patent: WO-01/09341 (2001-02-01), None
patent: WO-01/09711 (2001-02-01), None
patent: WO-01/18627 (2001-03-01), None
patent: WO-01/18627 (2001-03-01), None
patent: WO-01/23330 (2001-04-01), None
patent: WO-01/23601 (2001-04-01), None
patent: WO-01/23601 (2001-04-01), None
patent: WO-01/26038 (2001-04-01), None
patent: WO-01/40896 (2001-06-01), None
patent: WO-01/40896 (2001-06-01), None
patent: WO-01/55701 (2001-08-01), None
patent: WO-01/55719 (2001-08-01), None
patent: WO-01/57518 (2001-08-01), None
patent: WO-01/69247 (2001-09-01), None
patent: WO-01/69247 (2001-09-01), None
patent: WO-01/73672 (2001-10-01), None
patent: WO-01/78652 (2001-10-01), None
patent: WO-01/79515 (2001-10-01), None
patent: WO-01/84146 (2001-11-01), None
patent: WO-01/84146 (2001-11-01), None
patent: WO-02/04945 (2002-01-01), None
patent: WO-02/09836 (2002-02-01), None
patent: WO-02/22857 (2002-03-01), None
patent: WO-02/33377 (2002-04-01), None
patent: WO-02/052293 (2002-07-01), None
patent: WO-02/085195 (2002-10-01), None
patent: WO-02/085195 (2002-10-01), None
patent: WO-02/086452 (2002-10-01), None
patent: WO-02/086452 (2002-10-01), None
patent: WO-02/086478 (2002-10-01), None
patent: WO-02/086478 (2002-10-01), None
patent: WO-02/086500 (2002-10-01), None
patent: WO-02/086500 (2002-10-01), None
patent: WO-02/086501 (2002-10-01), None
patent: WO-02/086501 (2002-10-01), None
patent: WO-02/086502 (2002-10-01), None
patent: WO-2004/038381 (2004-05-01), None
patent: WO-2006/086731 (2006-08-01), None
Kell. Current Opinion in Microbiology, vol. 7, pp. 296-307. 2004.
Carney, M.W.P. et al., “Red cell folate concentrations in psychiatric patients,”Journal of Affective Disorders, vol. 19:207-213 (1990).
Gamache, Paul H. et al., “Metabolomic Applications of Electrochemistry/Mass Spectrometry,”J. Am. Soc. Mass Spectrom., vol. 15:1717-1726 (2004).
Hansen, Otto, “Blood Nucleoside and Nucleotide Studies in Mental Disease,”Brit. J. Psychiat., vol. 121:341-350 (1972).
Osher, Susan, “One-Carbon Metabolism in Adults with Major Depression,” Masters Thesis, University of Toronto (1999).
Plumb, Robert S. et al., “Metabonomics: the use of electrospray mass spectrometry coupled to reversed-phase liquid chromatography shows potential for the screening of rat urine in drug development,”Rapid Communications in Mass Spectrometry, vol. 16:1991-1996 (2002).
Trethewey et al, “Metabolic profiling: a Rosetta Stone for genomics?”Curr Opin Plant Biol, vol. 2(2):83-85 (1999).
Adams, Peter B. et al., “Arachidonic Acid to Eicosapentaenoic Acid Ratio in Blood Correlates Positively with Clinical Symptons of Depression,”Lipids, vol. 31(Suppl.):S157-S161 (1996).
Avery et al, “The use of lipid metabolic profiling to assess the biological impact of marine sewage pollution,”Arch Environ Contam Toxicol., vol. 35(2):229-235 (1998).
“Biochemicals, Organic Compounds and Diagnostic Reagents,” InSigma Catalog, p. 253 (1996).
Brindle et al, “Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using H-NMR-based metabonomics,”Nat. Med., vol. 8(12):1439-1444 (2002).
Buchholz et al, “Metabolomics: quantification of intracellular metabolite dynamics,”Biomol Eng., vol. 19(1):5-15 (2002).
Glassbrook et al, “Metabolic profiling on the right path,”Nat. Biotechnol., vol. 18(11):1142-1143 (2000).
Harrington, Michael G. et al., “Differences in Cerebrospinal Fluid Proteins between Patients with Schizophrenia and Normal Persons,”Clin. Chem., vol. 31(5):722-726 (1985).
Holmes et al, “Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks,”Chem. Res. Toxicol., vol. 14(2):182-191 (2001).
Kell, Douglas B., “Metabolomics and systems biology: making sense of the soup,”Current Opinion in Microbiology, vol. 7:296-307 (2004).
Matsumoto et al, “A new chemical diagnostic method for inborn errors of metabolism by mass spectrometry—rapid, practical, and simultaneous urinary metabolites analysis,”Mass Spectry Rev, vol. 15(1):43-57 (1998).
Nicholson, J.K. et al, “‘Metabonomics’: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data,”Xenobiotica, vol. 29(11):1181-1189 (1999).
Niebroj-Dobosz I, Janik P., ȁ
Kaddurah-Daouk Rima
Kristal Bruce S.
Benzion Gary
Calamita Heather G
Cornell Research Foundation Inc.
Hanley, Esq. Elizabeth A.
McCarter & English LLP
LandOfFree
Methods for drug discovery, disease treatment, and diagnosis... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for drug discovery, disease treatment, and diagnosis..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for drug discovery, disease treatment, and diagnosis... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4076859