Methods for downmodulating immune cells using an antibody to...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

Reexamination Certificate

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C424S143100, C424S144100, C435S375000, C435S377000, C530S387100, C530S388220

Reexamination Certificate

active

07029674

ABSTRACT:
Disclosed are methods for downmodulating an immune response comprising contacting an immune cell with an agent that modulates the interaction between PD-1 and a PD-1 ligand (e.g., soluble forms of PD-1 or PD-1 ligand or antibodies to PD-1) to thereby modulate the immune response.

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