Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Reexamination Certificate
2006-07-18
2006-07-18
Ponnaluri, Padmashri (Department: 1639)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
C435S091500, C435S006120, C435S069700, C435S320100, C435S091500, C530S387100
Reexamination Certificate
active
07078166
ABSTRACT:
The invention describes the display of exogenous polypeptides on filamentous phage using a fusion between the exogenous polypeptide and phage pVII or pIX proteins. In particular, phage particles and phagemid vectors are described for expression and display of heterodimeric proteins such as antibody Fv heterodimers in combinatorial libraries, and uses thereof.
REFERENCES:
patent: 5223409 (1993-06-01), Ladner et al.
patent: 5403484 (1995-04-01), Ladner et al.
patent: 5571698 (1996-11-01), Ladner et al.
patent: 5871974 (1999-02-01), Huse
patent: 5985588 (1999-11-01), Breitling et al.
patent: 6027930 (2000-02-01), Borrebaeck
patent: 6027933 (2000-02-01), Huse
patent: 6054312 (2000-04-01), LaRocca et al.
patent: 6127132 (2000-10-01), Breitling et al.
patent: 6172197 (2001-01-01), McCafferty et al.
Gao, et al., Making artificial antibodies: A format for phage display of combinatorial heterodimeric arrays, 1999,Proc. Natl. Acad. Sci. USA, 96:6025-6030.
Madison-Antenucci, et al., Translation limits synthesis of an assembly-initiating coat protein of filamentous phage IKe, 1998,J. Bacteriology, 180(3):464-472.
Gao Changshou
Janda Kim D.
Lerner Richard A.
Wirsching Peter
Fitting Thomas
Liu Sue
McCarthy Michael J.
Ponnaluri Padmashri
The Scripps Research Institute
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