Chemical apparatus and process disinfecting – deodorizing – preser – Process disinfecting – preserving – deodorizing – or sterilizing – Using disinfecting or sterilizing substance
Patent
1983-12-29
1985-08-27
Cintins, Ivars
Chemical apparatus and process disinfecting, deodorizing, preser
Process disinfecting, preserving, deodorizing, or sterilizing
Using disinfecting or sterilizing substance
422 37, A61L 216
Patent
active
045377464
ABSTRACT:
Improved methods of disinfecting and/or preserving contact lenses comprises treating said lenses with an effective concentration of a solution comprising a biguanide or a water soluble salt of the formula: ##STR1## wherein R.sub.1 and R.sub.3 are selected hydrogen, halogen, alkyl, alkoxy, nitro, --SO.sub.2 R.sub.4, carboxyl or hydroxyl where R.sub.4 is --NH.sub.2, --NHR', --NR'R", --OR' or --O--aryl in which R' and R" are alkyl or alkoxy; R.sub.2 is hydrogen or halogen and X is hydrogen or alkyl, provided that when R.sub.2 is halogen then both R.sub.1 and R.sub.3 are hydrogen and X is alkyl. The method provides for disinfecting and/or preserving contact lenses wherein the monomeric biguanide-containing solutions offer a wide spectrum of antimicrobial activity with nominal binding and concentrating onto lens surfaces and low levels of eye tissue irritation or inflammation.
REFERENCES:
patent: 4013576 (1977-03-01), Loshack
patent: 4354952 (1982-10-01), Riedhammer et al.
patent: 4388229 (1983-06-01), Fu
Ogunbiyi Lai
Scott Francis L.
Smith Francis X.
Bausch & Lomb Incorporated
Bogdon Bernard D.
Cintins Ivars
Croft Gregory E.
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