Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Reexamination Certificate
2007-04-09
2010-06-22
Gitomer, Ralph (Department: 1657)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
Reexamination Certificate
active
07741068
ABSTRACT:
The present invention relates to a method for differentiating in a subject suffering from chronic shortness of breath (dyspnea) between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease and (iv) dyspnea without cardiovascular or pulmonary causes. The method comprises the steps of determining an amount of a pulmonary surfactant protein in a sample of a subject, determining an amount of a natriuretic peptide in a sample of said subject, and differentiating between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease and (iv) chronic dyspnea without cardiovascular or pulmonary causes by comparing the amount determined in a) and the amount determined in b) with a reference amount for each. The present invention further provides a device and a kit for carrying out the inventive methods.
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Hess Georg
Horsch Andrea
Amick Marilyn
Gitomer Ralph
Roche Diagnostics Operations Inc.
Roche Diagnostics Operations Inc.
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