Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lipoproteins – e.g. – egg yolk proteins – cylomicrons – etc.
Patent
1994-05-16
1996-12-10
Fleisher, Mindy
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lipoproteins, e.g., egg yolk proteins, cylomicrons, etc.
530412, 435 4, 435 71, C07K 14435, C07K 114, A61K 3817, C12Q 100
Patent
active
055832016
ABSTRACT:
Methods of diagnosing peripheral nerve damage, including diagnosing and monitoring chronic back and cervical pain are disclosed. The methods involve subjecting a body fluid sample from a patient suspected of having chronic lumbar or cervical pain and peripheral nerve damage to two-dimensional electrophoresis or an immunoassay and measuring relative amounts of protein or proteins which increase or decrease in concentration as compared to a standard control. A preferred method employs an Apo-E variant as a marker of peripheral nerve damage. Also disclosed are kits for use with the diagnostic methods.
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Cameron, Sr. Bruce M.
Creed Guy J.
Merril Carl R.
VanderPutten Dale
Dagen Nancy J.
Fleisher Mindy
Monoclonetics International, Inc.
United States of America as represented by the Department of Hea
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