Methods for diagnosis of cardiovascular disease

Details Methods for diagnosis of cardiovascular disease Methods for diagnosis of cardiovascular disease

2001-11-08

2008-10-07

Landsman, Robert (Department: 1646)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S006120

Reexamination Certificate

active

07432060

ABSTRACT:
This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardiovascular conditions including cardiac hypertrophy, myocardial infarction, stroke, arteriosclerosis, and heart failure.

REFERENCES:
patent: 5217899 (1993-06-01), Shapiro et al.
patent: 5348879 (1994-09-01), Shapiro et al.
patent: 5786163 (1998-07-01), Hall
patent: 6288218 (2001-09-01), Levinson
patent: 6323334 (2001-11-01), Kingsbury et al.
patent: 2002/0072674 (2002-06-01), Criton et al.
patent: 2003/0124624 (2003-07-01), Tominaga et al.
patent: 2004/0048286 (2004-03-01), Lee
patent: 2006/0216755 (2006-09-01), Lee
patent: 6178687 (1994-06-01), None
patent: 7031479 (1995-02-01), None
patent: 98/07754 (1998-02-01), None
patent: WO 09/07754 (1998-02-01), None
patent: WO 98/38311 (1998-09-01), None
patent: 99/34217 (1999-07-01), None
patent: 00/35951 (2000-06-01), None
patent: WO 00/35473 (2000-06-01), None
patent: WO 00/73498 (2000-12-01), None
patent: WO 01/70817 (2001-09-01), None
patent: WO 02/38794 (2002-05-01), None
Saccani S, Polentarutti N, Penton-Rol G, Sims JE, and Mantovani A. 1998. Cytokine. vol. 10(10):773-780.
Kumar S, Maritsa MN, Griswold, DE, and Young PE. 1997. Biochem. Biophyl Res Comm. vol. 235:474-478.
Baumgarten G, Knuefermann P, Mann, DL. 2000. Trends Cardiovasc Med. vol. 10(5):216-223.
GenBank Submission: NIH/NCBI; Accession No. NP—003847, Feb. 3, 2006.
GenBank Submission: NIH/NCBI; Accession No. NP—003856, Feb. 3, 2006.
GenBank Submission: NIH/NCBI; Accession No. NP—057316, Feb. 3, 2006.
GenBank Submission: NIH/NCBI; Accession No. NP—016232, Feb. 3, 2006.
GenBank Submission: NIH/NCBI; Accession No. D13695, Feb. 3, 1999.
GenBank Submission: NIH/NCBI; Accession No. Y07519, Mar. 23, 1999.
GenBank Submission: NIH/NCBI; Accession No. AAA67172, May 23, 1995.
GenBank Submission: NIH/NCBI; Accession No. D12763, Feb. 1, 2000.
GenBank Submission: NIH/NCBI; Accession No. E07716, Sep. 29, 1997.
GenBank Submission: NIH/NCBI; Accession No. AB012701, Aug. 24, 2000.
GenBank Submission: NIH/NCBI; Accession No. AB029084, Oct. 31, 1999.
GenBank Submission: NIH/NCBI; Accession No.D12764, May 29, 2002.
GenBank Submission: NIH/NCBI; Accession No. U04319, May 24, 1995.
GenBank Submission: NIH/NCBI; Accession No. NM—013037, Apr. 15, 2005.
GenBank Submission: NIH/NCBI; Accession No. U04317, May 27, 1994.
GenBank Submission: NIH/NCBI; Accession No. E08652, Nov. 4, 2005.
GenBank Submission: NIH/NCBI; Accession No. AC007248, Apr. 21, 2005.
Office Action mailed Mar. 26, 2008 for U.S. Appl. No. 11/411,780 (B0801.70284US01).
Office Action mailed May 2, 2008 for U.S. Appl. No. 11/435,482 (B0801.70284US00).
Kuroiwa et al., Construction of ELISA system to quantify human ST2 protein in sera of patients. Hybridoma. Apr. 2000;19(2):151-9.
Shimpo et al., Serum levels of the interleukin-1 receptor family member ST2 predict mortality and clinical outcome in acute myocardial infarction. Circulation. May 11, 2004;109(18):2186-90.
Weinberg et al., Identification of serum soluble ST2 receptor as a novel heart failure biomarker. Circulation. Feb. 11, 2003;107(5):721-6. Online version published Jan. 13, 2003.
Weinberg et al., Expression and regulation of ST2, an interleukin-1 receptor family member, in cardiomyocytes and myocardial infarction. Circulation. Dec. 3, 2002;106(23):2961-6.
Aukrust et al., Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol. Feb. 1, 1999;83(3):376-82.
Brown, Techniques for mechanical stimulation of cells in vitro: a review. J Biomech. Jan. 2000;33(1):3-14. Review.
Cheng et al., Mechanical strain tightly controls fibroblast growth factor-2 release from cultured human vascular smooth muscle cells. Circ Res. Jan. 1997;80(1):28-36.
Coyle et al., Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. J Exp Med. Oct. 4, 1999(7):895-902.
De Keulenaer et al., Identification of IEX-1 as a biomechanically controlled nuclear factor-kappaB target gene that inhibits cardiomyocyte hypertrophy. Circ Res. Apr. 5, 2002;90(6):690-6.
Feng et al., Transcriptional profile of mechanically induced genes in human vascular smooth muscle cells. Circ Res. Dec. 3-17, 1999;85(12):1118-23.
Gwechenberger et al., Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions. Circulation. Feb. 2, 1999;99(4):546-51.
Hirota et al., Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell. Apr. 16, 1999;97(2):189-98.
Iwahana et al., Different promoter usage and multiple transcription initiation sites of the interleukin-1 receptor-related human ST2 gene in UT-7 and TM12 cells. Eur J Biochem. Sep. 1999;264(2):397-406.
Izakov et al., Cooperative effects due to calcium binding by troponin and their consequences for contraction and relaxation of cardiac muscle under various conditions of mechanical loading. Circ Res. Nov. 1991;69(5):1171-84.
Joyce et al., Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes. Eur J Immunol. Nov. 1994;24(11):2699-705.
Löhning et al., T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Natl Acad Sci U S A. Jun. 9, 1998;95(12):6930-5.
MacGowan et al., Circulating interleukin-6 in severe heart failure. Am J Cardiol. Apr. 15, 1997;79(8):1128-31.
Mann et al., Stress activated cytokines and the heart. Cytokine Growth Factor Rev. Dec. 1996;7(4):341-54.
Mitcham et al., T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family. J Biol Chem. Mar. 8, 1996;271(10):5777-83.
Murphy et al., Signaling and transcription in T helper development. Annu Rev Immunol. 2000;18:451-94.
Murray et al., Chronic beta-adrenergic stimulation induces myocardial proinflammatory cytokine expression. Circulation. May 23, 2000;101(20):2338-41.
Nichols et al., The influence of ‘diastolic’ length on the contractility of isolated cat papillary muscle. J Physiol. Apr. 1985;361:269-79.
Ng et al., Diagnosis of heart failure using urinary natriuretic peptides. Clin Sci (Lond). Feb. 2004;106(2):129-33.
Ohtsuka et al., Effect of beta-blockers on circulating levels of inflammatory and anti-inflammatory cytokines in patients with dilated cardiomyopathy. J Am Coll Cardiol. Feb. 2001;37(2):412-7.
O'Neill et al., The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense. Immunol Today. May 2000;21(5):206-9.
Potter et al., Mutations in the murine fitness 1 gene result in defective hematopoiesis. Blood. Sep. 1, 1997;90(5):1850-7.
Prabhu et al., beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling. Circulation. May 2, 2000;101(17):2103-9.
Pulkki et al., Cytokines and cardiomyocyte death. Ann Med. Aug. 1997;29(4):339-43.
Roig et al., Serum interleukin-6 in congestive heart failure secondary to idiopathic dilated cardiomyopathy. Am J Cardiol. Sep. 1, 1998;82(5):688-90, A8.
Schaffer et al., Device for the application of a dynamic biaxially uniform and isotropic strain to a flexible cell culture membrane. J Orthop Res. Sep. 1994;12(5):709-19.
Sutton et al., Left ventricular remodeling after myocardial infarction: pathophysiology and therapy. Circulation. Jun. 27, 2000;101(25):2981-8.
Tominaga et al., The existence of a growth-specific DNA binding factor for the promoter region of mouse ST2 gene. FEBS Lett. Nov. 14, 1994;354(3):311-4.
Tominaga et al., A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor. FEBS Lett. Dec. 4,

Affiliated with

Also associated with

Rating

Methods for diagnosis of cardiovascular disease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for diagnosis of cardiovascular disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for diagnosis of cardiovascular disease will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4006935