Methods for diagnosis and treatment of chronic immune diseases

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S004000, C435S007210, C435S023000, C436S063000, C436S086000, C436S506000, C436S811000

Reexamination Certificate

active

06989239

ABSTRACT:
Methods are provided for diagnosing/characterizing chronic immune disease activity in a subject. In the subject methods, a sample is obtained from a subject suspected of having or known to have a chronic immune disease. The sample is then assayed for the presence and amount of intact (i.e., native) p53 protein and/or fragments thereof. The assay results are used to diagnose the presence of chronic immune disease and/or characterize chronic immune disease activity in a subject, and/or to determine appropriate treatments protocols. Also provided by the subject invention are methods of treating chronic immune disease conditions by enhancing p53 activity. Also provided by the subject invention are kits for practicing the methods.

REFERENCES:
patent: 5538856 (1996-07-01), Levy et al.
patent: 5766859 (1998-06-01), Vojdani et al.
patent: 5776690 (1998-07-01), Vojdani et al.
patent: 5830668 (1998-11-01), Mordechai et al.
patent: 5853996 (1998-12-01), Mordechai et al.
patent: 5955263 (1999-09-01), Vogelstein et al.
patent: 5985565 (1999-11-01), Suhadolnik
patent: 6017524 (2000-01-01), Roth et al.
patent: 6051384 (2000-04-01), Zentgraf et al.
patent: 6090566 (2000-07-01), Vogelstein et al.
patent: 6110671 (2000-08-01), Kim
patent: 6140058 (2000-10-01), Lane et al.
patent: 6153391 (2000-11-01), Picksley et al.
patent: 6153591 (2000-11-01), Cai et al.
patent: 6169073 (2001-01-01), Halazonetis et al.
patent: 6184210 (2001-02-01), Keana et al.
patent: 6808936 (2004-10-01), Englebienne et al.
patent: 6824988 (2004-11-01), Roelens et al.
patent: WO 91/00097 (1991-01-01), None
Antel et al, Springer Seminars in Immunopathology, 17, 17-28, 1995.
Kawamata et al, American Jour. of Pathology, 140, 691-707, 1992.
Martin, Neurobiology of Disease, 7, 613-622, 2000.
The Merck Manual, 17th Edition, Merck Research Laboratories, 1999, pp. 1024-1026, 1041, 1061-1063.
Kastan et al., (1991), Cancer Res. 51:6304-6311.
Kuerbitz et al., (1992), Proc. Natl. Acad. Sci. 89:7491-7495.
Lowe et al., (1993), Cell, T4:957-987.
Clarke et al., (1993), Nature, 362:840-852.
Lowe et al., (1993), Nature, 362:847-849.
Pariat et al., (1997), Mol. Cell. Biol. 17(5):2805-2815.
Komaroff (2000), Am. J. Med., 105:169-171.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods for diagnosis and treatment of chronic immune diseases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for diagnosis and treatment of chronic immune diseases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for diagnosis and treatment of chronic immune diseases will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3556894

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.