Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1996-02-21
1999-06-15
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 794, 436 64, 436 86, G01N 33573
Patent
active
059121351
ABSTRACT:
The present invention relates to novel methods for diagnosing benign prostatic diseases (BPD), such as benign prostatic hyperplasia, prostatitis, or glandular atrophy, in a male human patient without requiring a biopsy. The total prostate specific antigen (PSA) level in the blood or serum of the patient is measured. If the patient has a total PSA level of between about 2.5 ng/ml and 10.0 ng/ml, then the free PSA level in the blood or serum of the patient is measured. The proportion of free PSA to total PSA is calculated. If this proportion is equal to or greater than about 25%, then the patient is diagnosed as having BPD. Optionally, if the patient has a total PSA level of between 10.1 ng/ml and 20.0 ng/ml, then the free PSA level in the blood or serum of the patient can also be measured. The proportion of free PSA to total PSA is calculated. If this proportion is equal to or greater than about 25%, then the patient is diagnosed as having BPD.
REFERENCES:
W.J. Catalona et al, Jour. Amer. Med. Assoc., 274, 1214-1220, 1995.
A. Christensson et al, Jour. Urol., 150, 100-105, 1993.
A.A. Luderer et al, Urology, 46, 187-194, 1995.
K. Mitrunen et al, Clin. Chem; 41, 1115-1120, 1995.
J.E. Osterling et al, Urol. Clin. North. Amer., 20, 671-680, 1993.
Carlson Grant D.
Kramp William J.
Luderer Albert A.
Soriano Thomas F.
Thiel Robert P.
Saunders David
Voyce Brian D.
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