Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-08-15
2006-08-15
Moran, Marjorie (Department: 1631)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S024300, C536S024320, C536S025300
Reexamination Certificate
active
07090972
ABSTRACT:
A method for preparing probes, as well as several probes for use in qualitative or quantitative hybridization assays are disclosed. The method comprises constructing an oligonucleotide that is sufficiently complementary to hybridize to a region of rRNA selected to be unique to a non-viral organism or group of non-viral organisms sought to be detected, said region of rRNA being selected by comparing one or more variable region rRNA sequences of said non-viral organism or group of non-viral organisms with one or more variable region rRNA sequences from one or more non-viral organisms sought to be distinguished. Hybridization assay probes forMycobacterium avium, Mycobacterium intracellulare, theMycobacterium tuberculosis-complex bacteria,Mycoplasma pneumoniae, Legionella, Salmonella, Chlamydia trachomatis, Campylobacter, Proteus mirabilis, Enterococcus, Enterobacter cloacae, E. coli, Pseudomonasgroup I,Neisseria gonorrhoeae, bacteria, and fungi also are disclosed.
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Hogan James John
Kop JoAnn
McDonough Sherrol Hoffa
Smith Richard Dana
Cappellari Charles B.
Fisher Carlos A.
Gen-Probe Incorporated
Heber Sheldon O.
Moran Marjorie
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