Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-11-28
2006-11-28
Le, Long V. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007920, C436S518000
Reexamination Certificate
active
07141382
ABSTRACT:
The present disclosure concerns methods of detecting a molecule, interleukin 18, in a sample, and using the detection of IL-18 to predict a condition. In a particular embodiment, the present invention concerns methods of detecting interleukin 18, in a sample, preferably prior to the increase in serum creatinine in a subject predisposed to a condition. In certain embodiments, the methods may comprise obtaining a sample from a subject such as a urine or blood sample and analyzing the sample for the presence or absence of IL-18 to predict a condition for example acute renal failure or organ transplant failure. In another embodiment, the methods may comprise analyzing a sample from a subject for the presence of IL-18 and applying information obtained from analyzing the presence of IL-18 to determine a treatment for a medical condition of the subject.
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Edelstein Charles L.
Parikh Chirag R.
Faegre & Benson LLP
Foster Christine E.
Le Long V.
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