Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1996-07-12
1999-01-12
Kunz, Gary L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
435 32, 536 172, C07H 304, C07H 306, C12Q 102, C12Q 110
Patent
active
058586989
ABSTRACT:
Therapeutic and diagnostic methods are provided for treatment and detection of enteropathogenic E. coli (EPEC) enteric infections. Also provided is an assay for the identification of compositions which are effective inhibitors of EPEC infection.
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Cravioto, et al., Inhibition of Localized Adhesion of Enteropathogenic Escherichia coli to Hep-2 by Immunoglobulin and Oligosaccharide Fractions of Human Colostrum and Breast Milk, JID, 1991:163 (Jun.).
Camara, et al., Inhibition of Enteropathogenic Escherichia coli (EPEC) Adhesion to HeLa Cells by Human Colostrum: Detection of Specific slqA Related to EPEC Outer-Membrane Proteins, Int Arch Allergy Immunology 1994;103:307-310.
Saletsky, et al., Isolation and Characterization of the Localized Adherence Factor of Enteropathogenic Escherichia coli, Infection and Immunity, Nov. 1988, pp. 2979-2983, vol. 56, No. 11.
Chart and Rowe, The outer membrane protein of enteropathogenic Escherichia coli, described as the `localised adherence factor`, is OmpF and probably not invovled in adhesioon to Hep-2 cells, FEMS Microbiology Letters, 61 (1989), 291-296.
Armstrong Glen D.
Vanmaele Rosa P.
Kunz Gary L.
University of Alberta
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