Methods for detection of a target nucleic acid by forming a...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C536S023100, C536S024300

Reexamination Certificate

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07838225

ABSTRACT:
The invention relates to and methods for generating a signal indicative of the presence of a target nucleic acid in a sample. The compositions and methods include a reverse transcriptase, a nuclease, an upstream primer and downstream probe.

REFERENCES:
patent: 4683194 (1987-07-01), Saiki
patent: 4683195 (1987-07-01), Mullis
patent: 4683202 (1987-07-01), Mullis
patent: 4775619 (1988-10-01), Urdea
patent: 4800159 (1989-01-01), Mullis
patent: 4818680 (1989-04-01), Collins et al.
patent: 4965188 (1990-10-01), Mullis
patent: 5030557 (1991-07-01), Hogan
patent: 5075216 (1991-12-01), Innis
patent: 5118605 (1992-06-01), Urdea
patent: 5118801 (1992-06-01), Lizardi
patent: 5124246 (1992-06-01), Urdea
patent: 5210015 (1993-05-01), Gelfand
patent: 5215899 (1993-06-01), Dattagupta
patent: 5288609 (1994-02-01), Engelhardt
patent: 5310652 (1994-05-01), Gelfand et al.
patent: 5380833 (1995-01-01), Urdea
patent: 5403711 (1995-04-01), Walder
patent: 5422253 (1995-06-01), Dahlberg
patent: 5424413 (1995-06-01), Hogan
patent: 5487972 (1996-01-01), Gelfand
patent: 5538848 (1996-07-01), Livak et al.
patent: 5541311 (1996-07-01), Dahlberg
patent: 5618703 (1997-04-01), Gelfand
patent: 5624802 (1997-04-01), Urdea
patent: 5654143 (1997-08-01), Mallet
patent: 5691142 (1997-11-01), Dahlberg
patent: 5710264 (1998-01-01), Drdea
patent: 5719028 (1998-02-01), Dahlberg
patent: 5792614 (1998-08-01), Western
patent: 5795763 (1998-08-01), Dahlberg
patent: 5804375 (1998-09-01), Gelfand
patent: 5837450 (1998-11-01), Dahlberg
patent: 5843654 (1998-12-01), Heisler
patent: 5843669 (1998-12-01), Kaiser
patent: 5846717 (1998-12-01), Brow
patent: 5849481 (1998-12-01), Urdea
patent: 5888780 (1999-03-01), Dahlberg
patent: 5981183 (1999-11-01), Takarada
patent: 5985557 (1999-11-01), Prudent
patent: 5994069 (1999-11-01), Hall
patent: 6001567 (1999-12-01), Brow
patent: 6090543 (2000-07-01), Prudent
patent: 6110677 (2000-08-01), Western
patent: 6150097 (2000-11-01), Tyagi
patent: 6187304 (2001-02-01), Jin et al.
patent: 6277570 (2001-08-01), Wood
patent: 6309834 (2001-10-01), Sutcliffe et al.
patent: 6350580 (2002-02-01), Sorge
patent: 6458535 (2002-10-01), Hall
patent: 6528254 (2003-03-01), Sorge
patent: 6548250 (2003-04-01), Sorge
patent: 6589743 (2003-07-01), Sorge
patent: 6893819 (2005-05-01), Sorge
patent: 7118860 (2006-10-01), Sorge
patent: 7183052 (2007-02-01), Sorge
patent: 7189508 (2007-03-01), Sorge
patent: 7276597 (2007-10-01), Sorge
patent: 7309573 (2007-12-01), Sorge
patent: 7361467 (2008-04-01), Sorge et al.
patent: 7361469 (2008-04-01), Sorge
patent: 7381532 (2008-06-01), Sorge
patent: 7468251 (2008-12-01), Sorge
patent: 7482121 (2009-01-01), Sorge
patent: 7504218 (2009-03-01), Happe
patent: WO91/09950 (1991-11-01), None
patent: WO92/06200 (1992-04-01), None
patent: WO92/02638 (1992-12-01), None
patent: WO94/29482 (1994-12-01), None
patent: WO96/20287 (1996-07-01), None
patent: WO96/40999 (1996-12-01), None
patent: WO97/27214 (1997-07-01), None
patent: WO98/23774 (1998-06-01), None
patent: WO98/42873 (1998-10-01), None
patent: WO98/50403 (1998-11-01), None
Lyamichev et al., Structure-specific endonucleolytic cleavage of nucleic acids by eubacterial DNA polymerases. Science 260 : 778-783 (1993).
Harrington et al. Functional domains with FEN-1 and RAD2 define a family of structure- specific endonucleases : implications for nucleotide excision repair. Genes & Development 8 : 1344-1355 (1994).
Guatelli et al., Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication PNAS 87 : 1874-1878 (1990).
Whiting et al., Strand displacement synthesis capability of Moloney murine leukemia virus reverse transcriptase. J Virology 68(8): 4747-4758 (1998).
Hottiger et al., Strand displacement activity of the human immunodeficiency virus type 1 reverse transcriptase heterodimer and its individual subunits. Jouirnal of Biological Chemistry 269 (2) : 956-991 (1994).
Turchi, et al. “Completion of Mammalian Lagging Strand DNA Replication Using Purified Proteins” J. Biol Chem. 268 (20):15136-141 (1993).
Turchi, et al., “Enzymatic completion of mammalian lagging-strand DNA replication,” Proc. Natl. Acad. Sci. USA 91:9803-9807 (1994).
Urdea, et al. “A novel method for the rapid detection of specific nucleotide sequences in crude biological samples without blotting or radioactivity; application to the analysis if hepatitis B virus in human serum,” Gene 61:253-264 (1987).
Xu, et al., “Biochemical and Mutational Studies of the 5′-3′ Exonuclease of DNA Polymerase 1 ofEscherichia coli,” J. Mol. Biol. 268:284-302 (1997).
Behrens et al., Identification and properties of the RNA-dependent RNA polymerase of hepitis C Virus. EMBO J. 15 (1) :12-22 (1996).
Agrawal (ed.)Methods in Molecular Biology, vol. 20 : Protocols for Oligonucleotides and Analogs, Humana Press, pp. 165-189 (1993).
Agrawal, et al. “Modified oligonucleotides as therapeutic and diagnostic agents,” Current Opinion in Biotechnology, 6:12-19 (1995).
Bambara, et al., “Enzymes and Reactions at the Eukaryotic DNA Replication Fork,” J. Biol. Chem. 272:4647-4650 (1997).
Bardwell, et al., “Specific Cleavage of Model Recombination and Repair Intermediates by the Yeast Rad1-Rad10 DNA Endonuclease,” Science 265:2082-2085 (1994).
Barnes, et al., “Mechanism of Tracking and Cleavage of Adduct-damaged DNA Substrates by the Mammalian 5′- to 3′Exonuclease /Endonuclease RAD2 Homologue 1 or Flap Endonuclease 1”, J. Biol. Chem. 271:29624-29632 (1996).
Bebenek, et al. “The effects of dNTP pool imbalances on frameshift fidelity during DNA replication” J Biol Chem. 267 (6):3589-96 (1992).
Bergseid, et al., “A High Fidelity Thermostable DNA Polymerase Isolated from Pyrococcus Furiosus” Strategies 4:34-35 (1991).
Bhagwat, et al. “The 5'-Exonuclease Activity of Bacteriophage T4 RNase H is Stimulated by the T4 Gene 32 Single-stranded DNA-binding Protein, but Its Flap Endonuclease Is Inhibited,” J. Biol. Chem. 272:28523-28530 (1997).
Bonch-Osmolovskaya, et al. “Charachteristics of Desulfurococcus Amylolyticas N. Sp.—A New Extremely Thermophilic Archaebacterium Isloated From Thermal Springs of Kamchatka and Kunashir Island” Microbiology (Engl. Transl. of Mikrobiologiya) 57:78-85 (1988).
Brow, et al. “Differentiation of Bacterial 16S rRNA Genes and Intergenic Regions andMycobacterium tuberculosiskatG Genes by Structure-Specific Endonuclease Cleavage,” J. of Clin. Micro. 34:3129-3137 (1996).
Brutlag, et al. “An Active Fragment of DNA Polymerase Produced By Proteolytic Cleavage,” Biochem. Biophys. Res. Commun. 37:982-989 (1969).
Carballeira, et al., “Purification of a Thermostable DNA Polymerase fromThermus thermophilusHB8, Useful in the Polymerase Chain Reaction,” Biotechniques 9:276-281 (1990).
Cargill, et al. “Characterization of single-nucleotide polymorphisms in coding regions of human genes” Nature Genetics, 22: 231-8 (1999).
Ceska, et al. “Structure-specific DNA cleavage by 5′ nucleases” TIPS 23 (1998).
Clark “Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases” Nucl. Acids Res. 16(20):9677-86 (1988).
Copley, et al. “Exonuclease Cycling Assay: An Amplified Assay for the Detection of Specific DNA Sequences” BioTechniques 13:888-891 (1992).
Creighton, et al. “Base mispair extension kinetics. Binding of avian myeloblastosis reverse transcriptase to matched and mismatched base pair termini” J. Biol. Chem. 267(4):2633-39 (1992.
Defrancesco “The Next New Wave in Genome Analysis” The Scientist, 12(21):1-3 (1998).
Demott, et al., “Human RAD2 Homolog 1 5′-3′-Exo/Endonuclease Can Efficiently Excise a Displaced DNA Fragment Containing a 5′-Terminal Abasic Lesion by Endonuclease Activity,” J. Biol. Chem. 271:30068-30076 (1996).
Duck, et al. &

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