Methods for detecting weakly immunogenic analytes

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S009100, C424S130100, C424S178100, C530S387100, C436S512000, C436S514000, C436S540000

Reexamination Certificate

active

11591302

ABSTRACT:
GPE antibodies recognize GPE with high specificity. When used in a radioimmunoassay, they reliably measure the concentration of GPE. They may be used to extend the half-life of GPE both in vivo and in vitro, and in methods of purifying the GPE receptor. Two methods of rpHPLC accurately revolve GPE on the basis of its hydrophobicity.

REFERENCES:
patent: 4444879 (1984-04-01), Foster et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 6187906 (2001-02-01), Gluckman et al.
patent: 2002/0151522 (2002-10-01), Alexi
patent: 2003/0027760 (2003-02-01), Gluckman et al.
patent: 0366 638 (1990-05-01), None
patent: WO 95/17204 (1995-06-01), None
patent: WO 98/14202 (1998-04-01), None
patent: WO 99/65509 (1999-12-01), None
Tooyama et al., Production and immunohistochemical application of antiserum against Tyr-D-Ala-Phe, a N-terminal tripeptide common to dermorphin/deltorphin family. Peptides, 21, 2000, pp. 1649-1655.
Brennan, et al., “Chondroitin/Dematan Sulfate Proteoglycan in Human Fetal Membranes.” The Journal of Biological Chemistry, Nov. 25, 1984, 259 (22), pp. 13742-13750.
Millan et al., “Seminoma-derived Nagao isozyme is encoded by germ-cell alkaline phosphatease gene.” Proc. Natl. Acad. Sci. USA, vol. 85, May 1988, pp. 3024-3028.
Ballard, F. J. et al., “DS(1-3) IGF-I: A Truncated Form of Insulin-Like Growth Factor-I.” International Journal of Biochemistry and Cell Biology, Exeter, GB, vol. 28, No. 10, 1996, pp. 1085-1087, XP002952721 ISSN: 1357-2725.
Saura, J. et al., “Neuroprotective Effects of Gly-Pro-Glu, the N-terminal tripeptide of IGF-1, in the hippocampus in vitro.” Neuroreport. 1999, vol. 10, pp. 161-164, esp. p. 162, results.
Nilsson-Hakansson, et al. “Effects of IGF-1, truncated IGF-1 and the tripeptide Gly-Pro-Glu on acetylcholine release from parietal cortex of rat brain.” Neuroreport. Aug. 6, 1993, vol. 4, No. 9, pp. 1111-1114.
Gelboin, H., “Cytochrome P450 and Monoclonal Antibodies.” Pharmacological Reviews. 1993, vol. 45, No. 4, pp. 413-453, see entire document.
Vicki R. Sara, et al., “Identification of GLY-PRO-GLU (GPE), The Aminoterminal Tripeptide of Insulin-Like Growth Factor I Which Is Truncated In Brain, As A Novel Neuroactive Peptide.” Biochemical and Biophysical Research Communications, vol. 165, No. 2, Dec. 15, 1989, pp. 766-771.
Jose Luis Millan, et al., “Seminoma-Derived Nagao Isozyme Is Encoded by a Germ-Cell Alkaline Phosphatase Gene,” Proc. National Academy of Science USA, Developmental Biology, vol. 85, May 1988, pp. 3024-3028.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods for detecting weakly immunogenic analytes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for detecting weakly immunogenic analytes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for detecting weakly immunogenic analytes will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3886101

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.