Methods for detecting pathogen specific nucleic acids in urine

Details Methods for detecting pathogen specific nucleic acids in urine Methods for detecting pathogen specific nucleic acids in urine

2011-03-29

2011-03-29

Johannsen, Diana B (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200, C435S091500, C435S091520, C536S024330

Reexamination Certificate

active

07914982

ABSTRACT:
The invention is based upon the discovery that small nucleic acids from non-viral pathogens are able to cross the kidney and are present in urine of a subject when the subject is infected with the non-viral pathogen. These transrenal DNAs are especially prevalent at smaller sizes under about 300 bp. Thus the invention provides compositions and methods for the diagnosis of infection of a subject with non-viral pathogens through the detection of transrenal nucleic acids from those pathogens in the urine of the subject.

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