Methods for detecting organisms and enzymatic reactions...

Details Methods for detecting organisms and enzymatic reactions... Methods for detecting organisms and enzymatic reactions...

2011-05-24

2011-05-24

Navarro, Mark (Department: 1645)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C356S301000

Reexamination Certificate

active

07947437

ABSTRACT:
The present disclosure provides systems for the rapid and sensitive detection of organisms and molecules in samples. Reactants that produce Raman-active products are used in combination with Raman light scattering. The present disclosure can also be used to measure enzyme-kinetics.

REFERENCES:
patent: 2003/0059820 (2003-03-01), Vo-Dinh
patent: 2008/0274489 (2008-11-01), Siegel et al.
patent: 0 714 025 (1996-05-01), None
patent: 0 725 271 (1996-08-01), None
patent: 9-222395 (1997-08-01), None
patent: 2000258346 (2000-09-01), None
patent: WO 2004/007767 (2004-01-01), None
patent: WO 2006/096468 (2006-09-01), None
patent: WO 2006/104695 (2006-10-01), None
patent: WO 2007/011778 (2007-01-01), None
patent: WO 2007/047526 (2007-04-01), None
patent: WO 2008/018933 (2008-02-01), None
Partial International Search Report in Application No. PCT/US2009/033750.
Dou, X “Enzyme Immunoassay Utilizing Surface-Enhanced Raman Scattering of the Enzyme Reaction Product,” Anal. Chem. 69: 1492-45 (1997).
Office Action mailed on Apr. 21, 2009 in related U.S. Appl. No. 11/580,845.
European Exam Report for European Application No. 06 816 934.1, dated Sep. 16, 2008.
Driskell, J.D., et al., “Low-Level Detection of Viral Pathogens by a Surface-Enhanced Raman Scattering Based Immunoassay,” 77(19) Analytical Chemistry, 6147-6154 (2005).
Grow, A., et al., “New Biochip Technology for Label-Free Detection of Pathogens and Their Toxins,” 53(2) Journal of Microbiological Methods, 221-223 (2003).
Mosier-Boss, P.A., “Optical Properties of Surface-Enhanced Raman-Active Capture Matrices,” 60(10) Applied Spectroscopy, 1148-1156 (2006).
Mosier-Boss, P.A., et al., “Surface-Enhanced Raman Spectroscopy Substrate Composed of Chemically Modified Gold Colloid Particles Immobilized on Magnetic Microparticles,” 77(4) Analytical Chemistry, 1031-1037 (2005).
Sengupta, A., et al., “Bioaerosol Characterization by Surface-Enhanced Raman Spectroscopy (SERS),” 36(5-6) Journal of Aerosol Science; Measurement and Characterization of Bioaerosols, 651-664 (2005).
Xu Shuping et al., “Surface-Enhanced Raman Scattering Studies on Immunoassay,” 10(3) Journal of Biomedical Optics, 1-12 (2005).
Plastino et al “An Unexpected Role for the Active Site Base in Cofactor Orientation and Flexibility in the Copper Amine Oxidase fromHansenula polymopha,” Biochemistry 38: 8204-16 (1999).
Rathore et al. “Direct Observation and Structural Characterization of the Encounter Complex in Bimolecular Electron Transfers with Photoactivated Acceptors,” J. Am. Chem. Soc. 119: 11468-11480 (1997).
Durckheimer, W. et al., “The Oxidative Conversion of Hydroquinone Monophosphates to Quinone Ketals,” Biochemistry, 3:1948-1952 (1964).
Ivnitski, D., et al., “Biosensors for detection of pathogenic bacteria,” Biosensors & Bioelectronics, 14:599-624 (1999).
Másson, M. et al., “4-Amino-1-naphthylphosphate as a substrate for the amperometric detection of alkaline phosphatase activity and its application for immunoassay,” Talanta, 64:174-180 (2004).
Másson, M. et al., “4-Hydroxynaphthyl-1-phosphate as a substrate for alkaline phosphatase and its use in sandwich immunoassay,” Analytica Chimica Acta, 402 (1999) 29-35.
Santandreu, M. et al., “Amperometric Immunosensors Based on Rigid Conducting Immunocomposites,” Analytical Chemistry, 69:2080-2085 (1997).
Tang, H. et al., “p-Aminophenyl Phosphate: An Improved Substrate for Electrochemical Enzyme Immunoassy,” Analytica Chimica Acta, 214:1987-195 (1988).
Wilson, M. et al., “Hydroquinone diphosphate: an alkaline phosphatase substrate that does not produce electrode fouling in electrochemical immunoassays,” Biosensors & Bioelectronics, 20:276-283 (2004).

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