Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-02-28
1999-11-02
Myers, Carla J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, 435 9152, 536 235, 536 2431, 536 2433, C12Q 168, C12P 1934, C07H 2104
Patent
active
059767987
ABSTRACT:
The present invention relates to methods of detecting genetic mutations in mitochondrial cytochrome oxidase c genes that segregate with Alzheimer's Disease and methods for determining the amount of heteroplasmy of mitochondrial nucleic acid. The invention provides methods for detecting such mutations, as a diagnostic for Alzheimer's Disease, either before or after the onset of clinical symptoms.
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Fahy Eoin D.
Ghosh Soumitra
Herrnstadt Corinna
Parker William Davis
Mitokor
Myers Carla J.
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