Chemistry: analytical and immunological testing – Nuclear magnetic resonance – electron spin resonance or other...
Reexamination Certificate
2011-07-05
2011-07-05
Warden, Jill (Department: 1773)
Chemistry: analytical and immunological testing
Nuclear magnetic resonance, electron spin resonance or other...
C436S127000, C436S131000
Reexamination Certificate
active
07972868
ABSTRACT:
Provided are methods of detecting the presence or amount of a dihydroxyvitamin in D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydroxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay.
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Caston-Balderrama Anne
Clarke Nigel J.
Holmquist Brett
Reitz Richard E.
Cole Monique
Foley & Lardner LLP
Quest Diagnostics Investments Incorporated
Warden Jill
LandOfFree
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