Methods for detecting contamination in molecular diagnostics...

Details Methods for detecting contamination in molecular diagnostics... Methods for detecting contamination in molecular diagnostics...

2005-01-18

2005-01-18

Horlick, Kenneth R. (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200, C435S091100, C435S091510, C536S025320

Reexamination Certificate

active

06844155

ABSTRACT:
The invention provides methods for detecting contamination in a PCR reaction. Methods of the invention are especially useful for detection of contamination in heterogeneous samples containing a rare nucleic acid to be detected.

REFERENCES:
patent: 4965188 (1990-10-01), Mullis et al.
patent: 5882856 (1999-03-01), Shuber
patent: 6518026 (2003-02-01), Hartley
patent: 0 415 755 (1991-03-01), None
patent: 9115601 (1991-10-01), None
patent: WO 9115601 (1991-10-01), None
patent: WO 9117270 (1991-11-01), None
Shuber et al., “A Simplified Procedure for Developing Multiplex PCRs,”Genome Research, vol. 5 (1995), pp. 488-493.
Weighardt et al., “A Simple Procedure for Enhancing PCR Specificity,”PCR Methods and Applications, vol. 3, No. 1 (Aug. 1993), pp. 77-81.

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