Methods for detecting catecholamines by mass spectrometry

Radiant energy – Ionic separation or analysis – Methods

Reexamination Certificate

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Reexamination Certificate

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07952068

ABSTRACT:
Provided are methods for determining the amount of one or more of one or more of epinephrine (E), norepinephrine (NE), and dopamine (D) in a sample using mass spectrometry. The methods generally involve ionizing one or more of E, NE, and D in a sample and detecting and quantifying the amount of the ion to determine the amount of one or more of E, NE, and D in the sample.

REFERENCES:
patent: 5772874 (1998-06-01), Quinn et al.
patent: 5795469 (1998-08-01), Quinn et al.
patent: 5919368 (1999-07-01), Quinn et al.
patent: 5968367 (1999-10-01), Quinn et al.
patent: 6107623 (2000-08-01), Bateman et al.
patent: 6124137 (2000-09-01), Hutchens et al.
patent: 6204500 (2001-03-01), Whitehouse et al.
patent: 6268144 (2001-07-01), Köster
patent: 6623928 (2003-09-01), Van Ness et al.
patent: 2006/0183238 (2006-08-01), Nimkar et al.
Bartolucci, et al., Liquid chromatography tandem mass spectrometric quantitation of sulfamethazine and its metabolites: direct analysis of swine urine by triple quadrupole and by ion trap mass spectrometry,Rapid Commun. Mass Spectrom. 14:967-73 (2000).
Carrera, V., et al., A simple and rapid HPLC-MS method for simultaneous determination of epinephrine, norepinephrine, dopamine and 5-hydroxytryptamine: Application to the secretion of bovine chromaffin cell cultures,J Chromatog. B, 847:88-94 (2007).
Chan, E., et al., High-performance liquid chromatographic assay for catecholamines and metanephrines using fluorimetric detection with pre-column 9-fluorenylmethyloxycarbonyl chloride derivatization,J Chromatog. B, 749:179-189 (2000).
Chan, E., et al., High-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometric method for the analysis of catecholamines and metanephrines in human urine,Rapid Commun. Mass Spectrom., 14:1959-1964 (2000).
Eriksson, B., et al., Determination of catecholamines in urine by liquid chromatography and electrochemical detection after on-line sample purification on immobilized boronic acid,J Chromatog., 593:185-190 (1992).
Gu, Q., et al., Analysis of catecholamines and their metabolites in adrenal gland by liquid chromatography tandem mass spectrometry,Analytica Chimica Acta, 609:192-200 (2008).
Heki, N., et al., Mass fragmentography—An improved method for the simultaneous analysis of norepinephrine, epinephrine and dopamine ant the pictogram level by mass fragmetography,Nippon Naibunpi Gakkai Zasshi, 53:785-96 (1977). (The article is in Japanese but an English language abstract has been provided).
Kushnir, M., et al., Analysis of Catecholamines in Urine by Positive-Ion Electrospray Tandem Mass Spectrometry,Clin. Chem., 48:323-31 (2002).
Lemos-Amado, F., et al., Electrospray tandem mass spectrometry of aminochromes,Rapid Commun. Mass Spectrom., 15:2466-71 (2001).
Merchant and Weinberger, Recent advancements in surface-enhancer laser desorption/ionization of flight-mass spectrometry,Electrophoresis, 21: 1164-67 (2000).
Polson et al., Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography—tandem mass spectrometry,Journal of Chromatography B, 785:263-275 (2003).
Robb et al., Atmospheric Pressure Photoionization: An Ionization Method for Liquid Chromatography-Mass Spectrometry,Anal. Chem., 72(15): 3653-3659 (2000).
Smythe, G., et al., Biochemical Diagnosis of Pheochromocytoma by Simultaneous Measurement of Urinary Excretion of Epinephrine and Norepinephrine,Clin. Chem., 38:486-92 (1992).
Soga, T., and Inoue, Y., Determination of catecholamines in urine and plasma by on-line sample pretreatment using an internal surface boronic acid gel,J Chromatog., 620:175-81 (1993).
Törnkvist, A., et al., Analysis of catecholamines and related substances using porous graphitic carbon as separation media in liquid chromatography-tandem mass spectrometry,J Chromatog. B, 801:323-329 (2004).
Wright et al., Proteinchip® surface enhanced laser desorption/ionization (SELDI) mass spectrometry: a novel protein biochip technology for detection of prostate cancer biomarkers in complex protein mixtures,Prostate Cancer and Prostatic Diseases, 2: 264-76 (1999).
Zimmer et al., Comparison of turbulent-flow chromatography with automated solid-phase extraction in 96-well plates and liquid-liquid extraction used as plasma sample preparation techniques for liquid chromatography-tandem mass spectrometry,J Chromatogr A, 854: 23-35 (1999).

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