Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-09-19
2006-09-19
Johannsen, Diana B. (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C435S287200
Reexamination Certificate
active
07108969
ABSTRACT:
Methods of monitoring the expression of genes in malignant oral cells is disclosed. Gene expression profiles are used to identify markers associated with malignant oral cells and to diagnose oral cancer.
REFERENCES:
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5384261 (1995-01-01), Winkler et al.
patent: 5424186 (1995-06-01), Fodor et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5556752 (1996-09-01), Lockhart et al.
patent: 5631734 (1997-05-01), Stern et al.
patent: 5677195 (1997-10-01), Winkler et al.
patent: 5708153 (1998-01-01), Dower et al.
patent: 5733729 (1998-03-01), Lipshutz et al.
patent: 5744305 (1998-04-01), Fodor et al.
patent: 5770358 (1998-06-01), Dower et al.
patent: 5770722 (1998-06-01), Lockhart et al.
patent: 5789162 (1998-08-01), Dower et al.
patent: 5800992 (1998-09-01), Fodor et al.
patent: 5856174 (1999-01-01), Lipshutz et al.
patent: 5874219 (1999-02-01), Rava et al.
patent: 5922591 (1999-07-01), Anderson et al.
patent: 5962237 (1999-10-01), Ts'o et al.
patent: 5981956 (1999-11-01), Stern
patent: 6013440 (2000-01-01), Lipshutz et al.
patent: 6013449 (2000-01-01), Hacia et al.
patent: 6025601 (2000-02-01), Trulson et al.
patent: 6033850 (2000-03-01), Purvis
patent: 6040138 (2000-03-01), Lockhart et al.
patent: 6040193 (2000-03-01), Winkler et al.
patent: 6043080 (2000-03-01), Lipshutz et al.
patent: 6045996 (2000-04-01), Cronin et al.
patent: 6050719 (2000-04-01), Winkler et al.
patent: 6171798 (2001-01-01), Levine et al.
Chang, D.D. et al. Characterization of transformation related genes in oral cancer cells. Ocnogene 16:1921-1930 (Apr. 1998).
Ibrahim, S.O. et al. Expression of biomarkers in oropharyngeal squamous cell carcinomas. Oral Oncology 35:302-313 (May 1999).
Alizadeh et al., “Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling,”Nature, 403:503-511 (2000).
Alon et al., “Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays,”Proc. Nat'l. Acad. Sci. U.S.A., 96:6745-50 (1999).
Barringer et al., “Blunt-end and single-strang ligations byEscherichia coliligase: . . . ,”Gene, 89:117 (1990).
Fodor et al., “Light-Directed, Spatially Addressable Parallel Chemical Synthesis,”Science, 251:767-772 (Feb. 14, 1991).
Golub et al., “Molecular Classification of Cancer: . . . ,”Science, 286:531-537 (1999).
Guatelli et al., “Isothermal,in vitroamplification of nucleic acids by a multienzyme reaction modeled after retroviral replication,”Proc. Natl. Acad. Sci U.S.A., 87:1874-1878 (1990).
Jourenkova-Mironova et al., “GlutathoneS- TransferaseGSTM1, GSTP1, andGSTT1Genotypes . . . ,”Int'l. J. Cancer, 81:44-48 (1999).
Katoh et al., “Genetic Polymorphisms of Tobacco- and Alcohol-Related Metabolizing Enzymes and Oral Cavity Cancer,”Int'l. J. Cancer, 83:606-609 (1999).
Kowh et al., “Transcription-based amplification system and detection of amplified human immunodeficiency virus type 1 with a bead-based sandwich hybridization format,”Proc. Natl. Acad. Sci U.S.A., 86:1173-1177 (1989).
Landegren et al., “A Ligase-Mediated Gene Detection Technique,”Science, 241:1077-1080 (1988).
Leethanakul et al., “Gene expression profiles in squamous cell carcinomas of the oral cavity: . . . ,”Oral Oncol., 36:474-483 (2000).
Lehninger,Principles of Biochemistry, pp. 793-800 (Worth Publishing, 1982).
Lockhart et al., “Expression monitoring by hybridization to high-density oligonucleotide arrays,”Nat'l. Biotechnol., 14:1675-1680 (1996).
Luo et al., “Gene expression profiles of laser-captured adjacent neuronal subtypes,”Nature Med., 5(1):117-122 (1999).
Mahadevappa and Warrington, “A high-density probe array sample preparation method using 10- to 100-fold fewer cells,”Nat'l. Biotechnol., 17:1134-1136 (1999).
Marshall, “Tumor Suppressor Genes,”Cell, 64:313-326 (1991).
Ohyama et al., “Laser Capture Microdissection-Generated Target Sample for High-Density Oligonucleotide Array Hybridization,”Biotechniques, 29(3):530-536 (2000).
Palazzolo et al., “Phage lambda cDNA cloning vectors for subtractive hybridization, fusion-protein synthesis and Creo-loxPautomatic plasmid subcloning,”Gene, 88:25-36 (1990).
Park et al., “CYP1AIandGSTM1Polymorphisms and Oral Cancer Risk,”Cancer Epidemiol. Biomarkers Prev., 6:791-797 (1997).
Perou et al., “Molecular portraits of human breast tumors,”Nature, 406:747-752 (2000).
Redfern et al., “Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy,”Proc. Nat'l. Acad. Sci. U.S.A., 97:4826-4831 (2000).
Sato et al., “Genetic polymorphism of drug-metabolizing enzymes and susceptibility to oral cancer,”Carcinogenesis, 20:1927-1931 (1999).
Sgroi et al., “In VivoGene Expression Profile Analysis of Human Breast Cancer Progression,”Cancer Res., 59:5656-5661 (1999).
Shillitoe et al., “Genome-wide analysis of oral cancer—early results from the Cancer Genome Anatomy Project,”Oral Oncol., 36:8-16 (2000).
Tamayo et al., “Interpreting patterns fo gene expression with self-organizing maps: Methods and application to hemotopoeitic differentiation,”Proc. Natl. Acad. Sci. U.S.A., 96:2907-2912 (1999).
Warrington et al., “Large-Scale Genomic Analysis Using Affymetrix GeneChip® Probe Arrays,”Microarray Biochip Technology, 6:119-148 (2000).
Weinberg, “Tumor Suppressor Genes,”Science254:1138-1146 (1991).
Wodicka et al., “Genome-wide expression monitoring inSaccharomyces cerevisiae,” Nat'l. Biotechnol., 15:1359-1367 (1997).
Wu and Wallace, “The Ligation Amplification Reaction (LAR)—Amplification of Specific DNA Sequences Using Sequential Rounds of Template-Dependent Ligation,”Genomics, 4:560-569 (1989).
Zhang et al., “Gene Expression Profiles in Normal and Cancer Cells,”Science, 276:1268-1272 (1997).
Janot et al., “Principal xenobiotic-metabolizing enzyme systems in human head and neck squamos cell carcinoma,”Carcinogensis, 14:1279-1283 (1993).
Junien et al., “Direct Gene Dosage Determination in Patients with Unbalanced Chromosomal Abberation using Cloned DNA Sequences . . . ,”Am. J. Hum. Genet., 35:584-591 (1983).
Kawamata et al., “Possible Contribution of Active MMP2 to Lymph-Node Metastasis and Secreted Cathepsin L to Bone Invasion of newly Established Human Oral-Squamous-Cancer Cell Lines,”Int. J. Cancer, 70:120-127 (1997).
Kimura et al., “Conventional tumor markers are prognostic indicators in patients with head and neck squamous cell carcinoma,”Cancer Lett., 155:163-168 (2000).
Kurokawa et al., “Manganese Superoxide Dismutase (Mn-SOD) Correlates with Prognosis of Patients with Oral Squamous Cell Carcinoma,”Fukuoka Igaku Zasshi, 39:321-327 (1998).
Lin and Chen, “Creating kinase isoenzymes activity in serum and buccal pouch tissue of hamsters during DMBA-induced squamos cell carcinogenesis,”J. Oral Pathol. Med., 20;479-485 (1991).
Liu et al., “Circulating Intercellular adhesion molecule 1 (ICAM-1), E-selectin and vascular cell adhesion molecule 1 (VCAM-1) in head and neck cancer,”Br. J. Cancer, 79:360-362 (1999).
Lotan et al., “Roles of Retinoids and their Nuclear Receptors in the Development and Prevention of Upper Aerodigestive Tract Cancers,”Environ. Health Perspect., 150(Suppl. 4):985-988 (1997).
Loukinova et al., “Growth Regulated Oncogene-α expression by murine squamous cell carcinoma promotes tumor growth, metastasis, leukocyte infiltration and angiogenesis by a host CXC Receptor-2 dependent mechanism,”Oncogene, 19:3477-3486 (2000).
Magary et al., “Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in laryngeal and ph
Mahadevappa Mamatha
Todd Charles Randolph
Warrington Janet A.
Wong David T. W.
Affymetrix Inc.
Johannsen Diana B.
President & Fellows of Harvard College
LandOfFree
Methods for detecting and diagnosing oral cancer does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for detecting and diagnosing oral cancer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for detecting and diagnosing oral cancer will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3579221