Methods for designing agents that interact with MMP-13

Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Chemical analysis

Reexamination Certificate

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C702S019000, C514S002600, C514S04400A, C703S011000

Reexamination Certificate

active

06934639

ABSTRACT:
The present invention relates to the three dimensional structure of human collagenase 3 (MMP-13), as well as to (i) methods of using the MMP-13 structure to rationally design or identify compounds or molecules that inhibit or activate MMP-13 activity, and (ii) compounds identified using said methods.

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