Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2007-11-13
2007-11-13
Sullivan, Daniel M. (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S471000, C435S173500, C435S173600
Reexamination Certificate
active
09815979
ABSTRACT:
Methods for delivering nucleic acid molecules into cells and methods for measuring nucleic acid delivery into cells and the expression of the nucleic acids are provided. The methods are designed for introduction of large nucleic acid molecules, including artificial chromosomes, into cells, and are practiced in vitro and in vivo.
REFERENCES:
patent: 4897355 (1990-01-01), Eppstein et al.
patent: 4937190 (1990-06-01), Palmenberg et al.
patent: 5208066 (1993-05-01), Fujisaki et al.
patent: 5288625 (1994-02-01), Hadlaczky
patent: 5318515 (1994-06-01), Wilk
patent: 5334761 (1994-08-01), Gebeyehu et al.
patent: 5389069 (1995-02-01), Weaver
patent: 5459127 (1995-10-01), Felgner et al.
patent: 5501662 (1996-03-01), Hofmann
patent: 5507724 (1996-04-01), Hofmann et al.
patent: 5550289 (1996-08-01), Eppstein et al.
patent: 5676151 (1997-10-01), Yock
patent: 5695967 (1997-12-01), Van Bokkelen et al.
patent: 5712134 (1998-01-01), Hadlaczky
patent: 5721118 (1998-02-01), Scheffler
patent: 5736392 (1998-04-01), Hawley-Nelson et al.
patent: 5747338 (1998-05-01), Giese et al.
patent: 5830430 (1998-11-01), Unger et al.
patent: 5837283 (1998-11-01), McDonald et al.
patent: 5843884 (1998-12-01), Sims
patent: 5853694 (1998-12-01), Engberts et al.
patent: 5869294 (1999-02-01), Harrington et al.
patent: 5891691 (1999-04-01), Hadlaczky
patent: 5944710 (1999-08-01), Dev et al.
patent: 5962265 (1999-10-01), Norris et al.
patent: 5965396 (1999-10-01), Pan et al.
patent: 5976796 (1999-11-01), Szalay et al.
patent: 5976849 (1999-11-01), Hustad et al.
patent: 5985577 (1999-11-01), Bulinski
patent: 5993434 (1999-11-01), Dev et al.
patent: 6025155 (2000-02-01), Hadlaczky et al.
patent: 6027488 (2000-02-01), Hofmann et al.
patent: 6034228 (2000-03-01), Norris et al.
patent: 6037133 (2000-03-01), Li
patent: 6054312 (2000-04-01), Larocca et al.
patent: 6074667 (2000-06-01), Kinnunen et al.
patent: 6077697 (2000-06-01), Hadlaczky et al.
patent: 6184037 (2001-02-01), Rolland et al.
patent: 6743967 (2004-06-01), Hadlaczky et al.
patent: 6936469 (2005-08-01), De Jong et al.
patent: 2002/0160410 (2002-10-01), Hadlaczky et al.
patent: 2002/0160970 (2002-10-01), Hadlaczky et al.
patent: 2003/0033617 (2003-02-01), Hadlaczky et al.
patent: 2003/0083293 (2003-05-01), Hadlaczky et al.
patent: 2003/0101480 (2003-05-01), Hadlaczky et al.
patent: 2003/0108914 (2003-06-01), Hadlaczky et al.
patent: 2003/0113917 (2003-06-01), De Jong et al.
patent: 2003/0119104 (2003-06-01), Perkins et al.
patent: 2003/0186390 (2003-10-01), De Jong et al.
patent: 2003/0224522 (2003-12-01), De Jong et al.
patent: 2004/0143861 (2004-07-01), Hadlaczky et al.
patent: 2004/0163147 (2004-08-01), Hadlaczky et al.
patent: 2004/0214290 (2004-10-01), Perez et al.
patent: 2005/0112661 (2005-05-01), De Jong et al.
patent: 2005/0153909 (2005-07-01), Hadlaczky et al.
patent: 2005/0181506 (2005-08-01), Perkins et al.
patent: 2006/0024820 (2006-02-01), Perkins et al.
patent: 2006/0095984 (2006-05-01), Hadlaczky et al.
patent: 2006/0143732 (2006-06-01), Perez et al.
patent: 2006/0150271 (2006-07-01), Hadlaczky et al.
patent: 2007/0061920 (2007-03-01), Hadlaczky et al.
patent: 0755924 (1997-01-01), None
patent: 0755924 (1999-06-01), None
patent: 9740183 (1997-10-01), None
patent: 9808964 (1998-03-01), None
patent: 9913719 (1999-03-01), None
patent: 9921584 (1999-05-01), None
patent: 99/54445 (1999-10-01), None
patent: 00/27795 (2000-05-01), None
patent: 0034436 (2000-06-01), None
patent: 02/076508 (2002-10-01), None
patent: 02/096923 (2002-12-01), None
patent: 02/097059 (2002-12-01), None
patent: 03/093469 (2003-11-01), None
Eck et al. (1996) Goodman & Gilman's The Pharmacological Basis of Therapeutics, 9th Edition, Chapter 5, McGraw-Hill, NY.
Orkin et al. (1995) Report and recommendations of the panel to assess the NIH investment in research on gene therapy, available through NIH or online at http://www.nih.gov
ews/panelrep/.
Strauss et al. Molecular complementation of a collagen mutation in mammalian cells using yeast artificial chromosomes. EMBO J. Feb. 1992;11(2):417-22.
Verma et al. Gene therapy—promises, problems and prospects. Nature. Sep. 18, 1997;389(6648):239-42.
Marshall E. Gene therapy's growing pains. Science. Aug. 25, 1995;269(5227):1050, 1052-5.
Ross et al. Gene therapy in the United States: a five-year status report. Hum Gene Ther. Sep. 10, 1996;7(14):1781-90.
Rissanen et al. Gene therapy for therapeutic angiogenesis in critically ischaemic lower limb—on the way to the clinic. Eur J Clin Invest. Aug. 2001;31(8):651-66.
Rubanyi GM. The future of human gene therapy. Mol Aspects Med. Jun. 2001;22(3):113-42.
Emanueli et al. Angiogenesis gene therapy to rescue ischaemic tissues: achievements and future directions. Br J Pharmacol. Aug. 2001;133(7):951-8.
Schwaab et al. Gene therapy of hemophilia. Semin Thromb Hemost. Aug. 2001;27(4):417-24.
Rosen FS. Successful gene therapy for severe combined immunodeficiency. N Engl J Med. Apr. 18, 2002;346(16):1241-3.
Somia et al. Gene therapy: trials and tribulations. Nat Rev Genet. Nov. 2000;1(2):91-9.
Houdebine et al. Transgenic animal bioreactors. Transgenic Res. 2000;9(4-5):305-20.
Mediatech, Inc. Formulations Table for Dulbecco's Modification of Eagle's Medium available at www.cellgrow.com.
Lipofectamine™ Reagent product description, available from Invitrogen™ life technologies.
Transfectam™ Reagent product description, available from Promega.
Marschall et al. Transfer of YACs up to 2.3 Mb intact into human cells with polyethylenimine. Gene Ther. Sep. 1999;6(9):1634-7.
1999 Press Releases: “Chromos Molecular Systems Reports In Vitro and In Vivo Stability of Functional Mammalian Artificial Chromosome”; http://www.chromos.com/march1899.htm1.
1999 Press Releases: “Chromos Molecular Systems Demonstrates Large-Scale Isolation of Mammalian Artificial Chromosomes”; http://www.chromos.com/feb399.htm1.
2001 Press Releases: “Chromos Announces Publication of Rapid Screening Technique in the Journal Cytometry”; http://www.chromos.com/June%207.htm1.
2001 Press Releases: “Chromos Presents New Chromosome-Based Platform Technology for Gene Therapy (ASGT)”; http://www.chromos.com/June%204.htm1.
2001 Press Releases: “Chromos Initates Research into Plant Artificia Chromosomes”; http://www.chromos.com/Jan23.htm1.
2001 Press Releases: “Chromos Announces Expression of Therapeutic Protein in Transgenic Animal Carrying an Artificial Chromosome”; http://www.chromos.com
ov8.htm1.
2001 Press Releases: “Chromos and Biological Research Center Announce Publication of Human Artificial Chromosome Methodology in the Journal of Cell Science”; http://www.chromos.com/sept12.htm1.
2001 Press Releases: “Chromos Reports Data on Transgenic Animals Carrying Artificial Chromosome”; http://www.chromos.com/march28.htm1.
Alton et al., “Nucleotide sequence analysis of the chloramphenicol resistance transposon Tn9”,Nature, 282:864-869 (1979).
Anderson et al., “Flow Cytometry of Mitotic Cells”,Experimental Cell Res., 238:498-502 (1998).
Audouy et al., “Serum as a modulator of lipoplex-mediated gene transfection: dependence of amphiphile, cell type and complex stability”,J. Gene Med., 2:465-476 (2000).
Baldwin et al., “Cloning of the Luciferase Structural Genes fromVibrio harveyiand Expression of Bioluminescence inEscherichia coli”, Biochem., 23:3663-3667 (1984).
Bao et al., “Transfection Of A Reporter Plasmid Into Cultured Cells By Sonoporation In Vitro”,Ultrasound in Med.&Biol., 23/6:953-959 (1997).
Basic Protocol, Book:Current Protocols in Molecular Biology, Supplement 14, “Calcium Phosphate Transfection”, Section 1, Unit 9.1.1-9.1.9.
Co et al., “Generation of transgenic mice and germline transmission of a mammalian artificial chromosome introduced into embryos by pronuclear microinjection”,Chromosome Res., 8:183-191 (2000).
Csonka et al., “Novel generation of human satellite DNA-based artificial
deJong Gary
Hoekstra Dirk
Oberle Volker
Vanderbyl Sandra Louise
Chromos Molecular Systems Inc.
Seidman Stephanie
Sullivan Daniel M.
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