Methods for constructing subarrays and subarrays made thereby

Details Methods for constructing subarrays and subarrays made thereby Methods for constructing subarrays and subarrays made thereby

2001-07-17

2009-12-01

Borin, Michael (Department: 1631)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S283100, C435S287200, C536S023100

Reexamination Certificate

active

07625697

ABSTRACT:
A method and device for detecting or monitoring the treatment status of a selected physiological state or disease condition. The device has a subarray of genes which show a statistically significant change in gene level expression when compared with the control expression levels for that gene. The method involves applying a reporter-labeled messenger nucleic acid fraction to the array in the device, and comparing the pattern of gene expression on the array with that produced by labeled messenger nucleic acid from control cells. Also disclosed is a method of constructing the array.

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