Methods for combatting renal toxicity due to metals or nephrotox

Details Methods for combatting renal toxicity due to metals or nephrotox Methods for combatting renal toxicity due to metals or nephrotox

1986-07-08

1988-07-19

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

A61K 3702

Patent

active

047585510

ABSTRACT:
The present invention relates to a method for combatting renal toxicity due to metals or nephrotoxic drugs. More specifically, the present invention relates to the administration of gamma-glutamyl amino acids to a subject so as to combat renal toxicity due to metals or nephrotoxic drugs. The present invention also relates to a method for selectively modulating in vivo formation of leukotriene types comprising administering gamma-glutamyl amino acids to a subject.

REFERENCES:
Methods of Enzymol., 113:555-564, (1984).
J. Chem. Soc., pp. 1959-1963, (1950).
J. Chem. Soc., pp. 886-894, (1957).
J. Biol. Chem., 248:2836-2844, (1973).
J. Amer. Chem. Soc., 75:4607-4608, (1953).

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