Methods for coating metal matrices for use in high gradient magn

Details Methods for coating metal matrices for use in high gradient magn Methods for coating metal matrices for use in high gradient magn

1994-05-31

1997-12-02

Jones, W. Gary

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

435 6, 435 5, 435 71, 435 79, 435527, 435 72, 435 721, 4352831, 4352886, 435824, 436803, 436526, 436 63, 436807, 252 6251, 252302, 2523152, 2523153, 422 57, 422 59, G01N 33553, G01N 33552, G01N 2100, C12Q 168

Patent

active

056935390

ABSTRACT:
Improvements in the existing procedures and materials for conduct of high gradient magnetic separation (HGMS) are disclosed. Superior superparamagnetic particles, optionally coated with a polysaccharide or other, usually organic, materials can be prepared in uniform compositions with homogeneous magnetizations. The coating can conveniently be conjugated to a specific binding moiety complementary to a biological material whose purification or separation is desired. In addition, plastic coated matrices which form superior magnetic gradient-intensifying supports are disclosed, along with improved methods and apparatus to conduct HGMS.

REFERENCES:
patent: 3911166 (1975-10-01), Bailey
patent: 4247398 (1981-01-01), Mohri
patent: 4375407 (1983-03-01), Kronick
patent: 4416380 (1983-11-01), Flum
patent: 5385707 (1995-01-01), Miltenyi et al.
patent: 5411863 (1995-05-01), Miltenyi

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