Methods for chemically synthesizing immunoglobulin chimeric...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S333000, C530S334000, C530S338000

Reexamination Certificate

active

07381408

ABSTRACT:
The invention provides methods of chemically synthesizing chimeric proteins comprising at least a portion of an immunoglobulin constant region and a biologically active molecule.

REFERENCES:
patent: 3941763 (1976-03-01), Sarantakis
patent: 4695623 (1987-09-01), Stabinsky
patent: 4784950 (1988-11-01), Hagen et al.
patent: 4897471 (1990-01-01), Stabinsky
patent: 5093246 (1992-03-01), Cech et al.
patent: 5116964 (1992-05-01), Capon et al.
patent: 5162220 (1992-11-01), Oshima et al.
patent: 5175096 (1992-12-01), Hook et al.
patent: 5189015 (1993-02-01), Hook et al.
patent: 5234830 (1993-08-01), Oshima et al.
patent: 5258498 (1993-11-01), Huston et al.
patent: 5428130 (1995-06-01), Capon et al.
patent: 5464933 (1995-11-01), Bolognsi et al.
patent: 5480981 (1996-01-01), Goodwin et al.
patent: 5482858 (1996-01-01), Huston et al.
patent: 5579277 (1996-11-01), Kelly
patent: 5585089 (1996-12-01), Queen et al.
patent: 5591573 (1997-01-01), Whalen et al.
patent: 5605689 (1997-02-01), Ammann
patent: 5648240 (1997-07-01), Hook et al.
patent: 5723125 (1998-03-01), Chang et al.
patent: 5739277 (1998-04-01), Presta et al.
patent: 5807706 (1998-09-01), Carter et al.
patent: 5808029 (1998-09-01), Brockhaus et al.
patent: 5869046 (1999-02-01), Presta et al.
patent: 5885821 (1999-03-01), Magota et al.
patent: 5910573 (1999-06-01), Pluckthun et al.
patent: 6013263 (2000-01-01), Barney et al.
patent: 6015881 (2000-01-01), Kang et al.
patent: 6017536 (2000-01-01), Barney et al.
patent: 6030613 (2000-02-01), Blumberg et al.
patent: 6060065 (2000-05-01), Barney et al.
patent: 6060613 (2000-05-01), Hattori et al.
patent: 6068973 (2000-05-01), Barney et al.
patent: 6086875 (2000-07-01), Blumberg et al.
patent: 6093799 (2000-07-01), Li et al.
patent: 6184344 (2001-02-01), Kent et al.
patent: 6228983 (2001-05-01), Barney et al.
patent: 6281331 (2001-08-01), Kang et al.
patent: 6310180 (2001-10-01), Tam
patent: 6310183 (2001-10-01), Johannessen et al.
patent: 6323323 (2001-11-01), Sledziewski et al.
patent: 6326468 (2001-12-01), Canne et al.
patent: 6329176 (2001-12-01), Woldike et al.
patent: 6469136 (2002-10-01), Bray et al.
patent: 6475491 (2002-11-01), Johnson et al.
patent: 6485726 (2002-11-01), Blumberg et al.
patent: 6660843 (2003-12-01), Feige et al.
patent: 2002/0081664 (2002-06-01), Lo et al.
patent: 2002/0106374 (2002-08-01), Olson et al.
patent: 2003/0053984 (2003-03-01), Tschopp et al.
patent: 2003/0180287 (2003-09-01), Gambotz et al.
patent: 2003/0235536 (2003-12-01), Blumberg et al.
patent: 2004/0077022 (2004-04-01), Feige et al.
patent: 2005/0027109 (2005-02-01), Mezo et al.
patent: 2005/0037947 (2005-02-01), Bitonti et al.
patent: WO 88/09810 (1988-12-01), None
patent: WO 89/10134 (1989-02-01), None
patent: WO 90/11364 (1990-10-01), None
patent: WO 00/18881 (2000-04-01), None
patent: WO 0018881 (2000-04-01), None
patent: WO 00/18881 (2000-05-01), None
patent: WO 01/02439 (2001-01-01), None
patent: WO 01/03737 (2001-01-01), None
patent: WO 01/58935 (2001-08-01), None
patent: WO 01/91780 (2001-12-01), None
patent: 02/18417 (2002-03-01), None
patent: WO 02/46208 (2002-06-01), None
patent: WO 02/089828 (2002-11-01), None
patent: WO 03/077834 (2003-09-01), None
patent: WO 03077834 (2003-09-01), None
patent: WO 2004/003176 (2004-01-01), None
patent: WO 2004/006962 (2004-01-01), None
patent: WO 2004/101740 (2004-11-01), None
patent: WO 2005/001025 (2005-01-01), None
European Search Report, European Patent Office, EP 04751356.9, Aug. 14, 2006.
Wilken, J., et al., Current Opinion in Biotechnology, 9(4):412-426 (1988).
U.S. Appl. No. 10/841,819, Rivera et al.
U.S. Appl. No. 10/841,956, Hehir et al.
Armour et al., “Recombinant human IgG molecules lacking Fc? receptor I binding and monocyte triggering activities,” Eur. J. Immunol., 29:2613-2624 (1999).
Bahlmann, Ferdinand H. et al., “Erythropoietin: is it more than correcting anaemia?,” Nephrol. Dial. Transplant., 19:20-22 (2004).
Barre-Sinoussi et al., Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS), Science 220:868 (1983).
Broze et al., “Purificaiton and Properties of Human Coagulation Factor VII,” J. Biol. Chem., 255:1242 (1980).
Burmeister et al., “Crystal structure at 2.2 A resolution of the MHC-related neonatal Fc receptor,” Nature, 372:323-324 (1994).
Carter et al., “Structure of Serum Albumin,” Adv. Prot. Chem. 45:153 (1994).
Chan et al., HIV Entry and Its Inhibition, Cell 93:681 (1998).
Clerc et al., “Primary structure control of recombinant proteins using high-performance liquid chromatography, mass spectrometry and microsequencing,” J. Chromatography 662:245 (1994).
Cohen et al., “Acquired inhibitors,” Bailiere's Clinical Hematology, 9(2):331 (1996).
Dagleish et al., The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus, Nature 312:763 (1984).
De Clerq et al., New Anti-HIV Agents and Targets, Med. Res. Rev. 22(6):531 (2002).
Dugaiczyk et al., “Nucleotide sequence and the encoded amino acids of human serum albumin mRNA,” Proc. Nat. Acad. Sci. USA 79:71 (1982).
Fischer et al., “The effects of postponing prophylactic treatment on long-term outcome in patients with severe hemophilia,” Blood, 99(7):2337 (2002).
Friend et al., “Phase I study of an engineered aglycosylated humanized CD3 antibody in renal transplant rejection,” Transplantation, 68:1632-1637 (1999).
Frostell-Karlsson et al., “Biosensor analysis of the interaction between immobilized human serum albumin and drug compounds for prediction of human serum albumin binding levels,” J. Med. Chem. 43:1986 (2000).
Gallo et al., Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patents with AIDS and at Risk for AIDS, Science 224:500 (1984).
Ghetie et al., “Multiple Roles for the Major Histocompatibility Complex Class I-Related Receptor FcRn,” Ann. Rev. Immunol. 18:739-66 (2000).
Hage et al., “Recent advances in chromatographic and electrophoretic methods for the study of drug-protein interactions,” J. Chromatography 699:499 (1997).
Hagen et al., “Characterization of a cDNA coding for human factor VII,” Proc. Natl. Acad. Sci. USA, 83:2412 (1986).
Hammarskjold et al., The molecular biology of the human immunodeficiency virus, Biochim. Biophys. Acta 989:269 (1989).
Israel et al., “Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells,” Immunol., 92:69-74 (1997).
Jelesarov et al., “Thermodynamic Characterization of the Coupled Folding and Association of Heterodimeric Coiled Coils (Leucine Zippers),” J. Mol. Biol., 263:344-358 (1996).
Johannessen et al., “Comparison of the factor VII:C clot analysis and a modified activated factor VII analysis for monitoring factor VII activity in patients treated with recombinant activated factor VII (NovoSeven®),” Blood Coagulation and Fibrinolysis, 11(Suppl. 1):S159 (2000).
Jones et al., “Replacing the complementarity-determining regions in a human antibody with those from a mouse,” Nature, 321:522-525 (1986).
Kang et al., “Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces,” Proc. Natl. Acad. Sci. USA, 88:4363-4366 (1991).
Kasper, “Hereditary plasma clotting factor disorders and their management,” Haemophilia, 6(Suppl. 1):13, (2000).
Kilby et al., Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry, Nat. Med. 4(11):1302 (1998).
Kobayashi et al., “FcRn-mediated transcytosis of immunoglobulin G in human renal proximal tubular epithelial cells,” Am. J. Physiol. Renal Physiol., 282:F358-F365 (2002).
Lemaitre et al., “Specific antiviral activity of a poly(L-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N protein mRNA initiation site,” Pr

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods for chemically synthesizing immunoglobulin chimeric... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for chemically synthesizing immunoglobulin chimeric..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for chemically synthesizing immunoglobulin chimeric... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2801989

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.