Methods for cardiac gene transfer

Details Methods for cardiac gene transfer Methods for cardiac gene transfer

2008-07-15

2008-07-15

Kaushal, Sumesh (Department: 1633)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S093100, C424S093200, C424S093600, C435S320100, C435S325000, C435S455000

Reexamination Certificate

active

09954571

ABSTRACT:
Methods for the delivery of genes to improve cardiac function including the use of viral vectors, isolation of the heart from systemic circulation, and induction of hypothermia/cardiac arrest are described. The method results in high-level, long-term expression of reporter genes and enhanced cardiac function in hamster models of heart disease.

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