Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2008-01-29
2008-01-29
Chunduru, Suryaprabha (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C530S350000
Reexamination Certificate
active
10295188
ABSTRACT:
The invention provides methods for prognosis, diagnosis, staging and disease progression in human cancer patients related to expression levels of a plurality of genes that are differentially expressed in chemotherapeutic drug resistant and drug sensitive tumor cells.
REFERENCES:
patent: 4996145 (1991-02-01), Weisenthal
patent: 5447842 (1995-09-01), Simons
patent: 5464753 (1995-11-01), Chaudhary et al.
patent: 5736129 (1998-04-01), Medenica et al.
patent: 5776747 (1998-07-01), Aebischer et al.
patent: 5834196 (1998-11-01), Reutelingsperger
patent: 5851789 (1998-12-01), Simon et al.
patent: 5994077 (1999-11-01), Valdivia et al.
patent: 5994088 (1999-11-01), Mechetner et al.
patent: 6004755 (1999-12-01), Wang
patent: 6040138 (2000-03-01), Lockhart et al.
patent: 6165709 (2000-12-01), Friend et al.
patent: 6333155 (2001-12-01), Lockhart et al.
patent: 6376169 (2002-04-01), Adams et al.
patent: 6406693 (2002-06-01), Thorpe et al.
patent: 6511806 (2003-01-01), Fruehauf et al.
patent: 6617426 (2003-09-01), Munoz et al.
patent: WO 9527903 (1995-10-01), None
patent: WO 99/50401 (1999-10-01), None
Palfner K et al. Differential display reveals PT1-1 and ribosomal Protein L4 involved in drug resistance and/or Robseration. Proc. Amer. Assoc. Cancer Res., vol. 38, p. 683.
Schultz et al. Identification and characterization of differentially expressed genes in various stages of development of Prostate Forms. Proc. Amer. Assoc. Cancer Res., vol. 38, p. 420, A2815, 1997.
Pervaiz et al. Caspase proteases mediate apoptosis induced by anticancer agent preactivated MC540 in human tumor cell lines. Cancer Letters, vol. 128, pp. 11-22, 1998.
Palfner et al. Differential display reveals PT1-1 and ribosomal protein involved in drug resistance and /or proliferation. Proc. Amer. Assoc. Cancer Research, vol. 38, p. 483, 1997.
Krishnakumar et al. Characterization of phosphatidylserine-dependent beta2-glycoprotein I macrophage interactions. J Biol. Chem., vol. 273, No. 44, pp. 29272-29277, 1998.
Palfner et al. Differential display reveals PT1-1 and ribosomal protein involved in drug resistance and /or proliferation. Proc. Amer. Assoc. Cancer Research, vol. 38, pp. 483, 1997.
Borgiani et al., “Comparative DNA analysis of breast cancer by flow cytometry and image analysis,” Pathologica (Genoa), 86(4):356-359, 1994.
Chen and Huang, “Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells,” British Journal of Pharmacology, 124(6):1029-1040, 1998.
Cordon-Cardo, “Immunohistochemical Analysis of P-Glycoprotein Expression in Normal and Tumor Tissues in Humans,” Molecular and Cellular Biology of Multidrug Resistance in Tumor Cells, pp. 303-318, 1991.
Gottesman et al., “Expression of the MDR1 Gene in Normal Human Tissues,” Molecular and Cellular Biology of Multidrug Resistance in Tumor Cells, Plenum Press, NY, pp. 279-289, 1991.
Gudkov et al., “Isolation of Genetic Suppressor Elements, Inducing Resistance to Topoisomerase II-Interactive Cytotoxic Drugs, from Human Topoisomerase II cDNA,” Proc. Natl. Acad. Sci. USA, 90:3231-3235, 1993.
Kern et al., “Highly specific prediction of antineoplastic drug resistance with an in vitro assay using suprapharmacologic drug exposures,” J. Nat. Cancer Inst., 82:582-588, 1990.
Lebow et al., “Analysis of Lymphocyte-Target Conjugates by Flow Cytometry I. Discrimination Between Killer and Non-Killer Lymphocytes Bound to Targets and Sorting of Conjugates Containing One or Multiple Lymphocytes,” Natural Immunity and Cell Growth Regulation, 5(5):221-237, 1986.
Maino et al., “Rapid flow cytometric method for measuring lymphocytes subset activation,” Cytometry, 20:127-133, 1995.
Mechetner et al., “Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubin,”Clin. Cancer Res., 4:389-98, 1998.
Orfao et al., “A new method for the analysis of plasma cell DNA content in multiple myeloma samples using a CD38/propidium iodide double staining technique,” Cytometry, 17(4):332-339, 1994.
Pepper et al., “BCL-2/BAX Ratios in chronic lymphocytic Leukaemia and their correlation with in vitro apoptosis and clinical resistance,” British Journal of Cancer, 76(7):935-938, 1997.
Seidl et al., “Evaluation of membrane physiology following flurescence activated or magnetic cell separation,” Cytometry, 36(2):102-111, 1999.
Arends et al., “Apoptosis. The role of the endonuclease,” Am. J. Pathol. 136(3):593-608, 1990.
Auerbach et al., “From Primitive Embryonic Precursor Cells To Organ and Tumor-Specific Vascular Endothelial Cells: A Progress Report,” Proc. Annu. Meet Am. Assoc. Cancer Res. 35:663, 1994.
Bange et al., “Molecular targets for breast cancer therapy and prevention ,” Nat. Med. 7(5):548-552, 2001.
Battegay, “Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects,” J. Mol. Med. 73(7):333-346, 1995.
Benelli et al., “In vitro models of angiogenesis: the use of Matrigel ,” Int. J. Biol. Markers 14(4):243-246, 1999.
Bertram, “The molecular biology of cancer,” Mol. Aspects Med. 21(6):167-223, 2000.
Bichsel et al., “Cancer proteomics: from biomarker discovery to signal profiling,” Cancer J. 7(1):69-78, 2001.
Bussolino e tal., “Molecular mechanisms of blood vessels formation,” Trends Biochem. Sc. 22(7):251-256, 1997.
Conrad-Lapostolle et al., “Optimization of use of UEA-1 magnetic beads for endothelial cell isolation,” Cell Biol. Toxicol. 12(4-6):189-197, 1996.
Coombes et al., “cDNA Array Analysis of Altered Gene Expression in Human Endothelial Cells in Response to Chlamydia pneumoniae infection,” Infect. Immunol. 69(3):1420-1427, 2001.
Diez et al., “Isolation of full-size mRNA from cells sorted by flow cytometry,” J. Biochem. Biophys. Methods 40(3):69-80, 1999.
Emmert-Buck et al., “Molecular Profiling of Clinical Tissue Specimens: Feasibility and Applications,” J. Mol. Diagn. 2(2):60-66, 2000.
Feng et al., “Transcriptional Profile of Mechanically Induced Genes in Human Vascular Smooth Muscle Cells,” Circ. Res. 85:1118-1123, 1999.
Folkman et al., “Angiogenesis,” J. Biol. Chem. 267(16):10931-10934, 1992.
Folkman, “Angiogenesis in cancer, vascular, rheumatoid and other disease,” Nat. Med. 1(1):27-31, 1995.
Gargett et al., “Isolation, characterization and long-term culture of human myometrial microvascular endothelial cells,” Hum. Reprod. 15(2):293-301, 2000.
Hewett et al. “Human microvessel endothelial cells: isolation, culture and characterization,” In Vitro Cell Dev. Biol. 29A(11):823-830, 1993.
Brunstein et al., “The biology and treatment of chronic myelogenous leukemia,” Oncology 15:23-31, 2001.
Ingber, “Fibronectin Controls Endothelial Cell Growth by Modulating Cell Shape,” Proc. Nat'l Acad. Sci. USA 87:3579-3583, 1990.
Joki et al., “Assessment of alteration in gene expression in recurrent malignant glioma after radiotherapy using complementary deoxyribonucleic acid microarrays,” Neurosurgery 48(1):195-202, 2001.
Jones et al., “The Current Status of Clinical Trials in Anti-Angiogenesis,” Principles and Practices of Oncology Updates 14(1):1-9, 2000.
Koong et al., “Candidates Genes for the Hypoxic Tumor Phenotype,” Cancer Res. 60:883-887, 2000.
Kumar et al., “CD 105 and angiogenesis,” J. Pathol. 178(4):363-366, 1996.
Laird et al., “SU6668 Is a Potent Antiangiogenic and Antitumor Agent That Induces Regression of Established Tumors,” Cancer Res. 60:4152-4160, 2000.
Li et al., “Blood-brain barrier genomics, ”J. Cereb. Blood Flow Metab. 21(1):61-68, 2001.
Li et al., “Positive and negative hematopoietic cytokines produced by bone marrow endothelial cells,
Fruehauf John P.
Mechetner Eugene
Chunduru Suryaprabha
McDonnell Boehnen & Hulbert & Berghoff LLP
Oncotech, Inc.
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