Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1997-04-11
1998-11-24
Huff, Sheela
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 435 72, 5303877, 5303897, G01N 3353
Patent
active
058405070
ABSTRACT:
The invention provides methods for prognosis, diagnosis, staging and disease progression in human cancer patients related to expression levels of a variety of immunohistochemical and genetic markers associated with poor cancer prognosis, and in particular those markers related to tumor invasiveness, metastasis and spread. The invention also provides methods using a predictive index for prognosis of cancer patients for metastasis, recurrence and relapse of neoplastic disease. The methods of the invention are useful for making clinical decisions on cancer treatment, surveillance and surgical intervention.
REFERENCES:
Iwaya et al Jpn Cancer Research vol. 82 835-840, Jul. 1991.
Zabrenetzky et al Int J Cancer VOI 59 191-195, 1994.
Gasparini et al Journal of Clinical Oncology VOI 13 No. 3 765-782, Mar. 1995.
Grossfeld et al Proceedings of the American Urological Association vol. 155 Supplement 688A Abstract 1508, May 1996.
Bevilacqua et al Breast Cancer Research and Treatment vol. 36 205-217, 1995.
Boring et al., (1992), Clin. J. Cancer, 42: pp. 19-38.
Mansour et al., (1989), N. Engl. J. Med., 320: 485-490.
Osbourne et al., (1992), J. Clin. Oncol., 679-682.
Allegra et al., (1979), Cancer Treat. Rep., 63: 1271-1277.
Von Rosen et al., (1989), Breast Cancer Res. Treat., 13: pp. 23-32.
Fisher et al., (1992), J. Natl. Cancer. Inst., 11: 152-258.
Clark et al., (1994), N.Engl. J. Med., 320: pp. 627-633.
Fisher et al., (1993), Cancer Medicine, 3.sup.rd Edition, Holland et al., pp. 1706-1774.
Early Breast Cancer Trialists Collaborative Group (1992), Lancet, 339: pp. 1-15.
The Ludwig Breast Cancer Study Group (1989), N. Engl. J. Med., 320: 491-496.
Gasparini et al., (1993), J. Natl. Cancer Inst., 85: 1206-1219.
Huff Sheela
Oncotech, Inc.
Reeves Julie E
LandOfFree
Methods for cancer prognosis and diagnosis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for cancer prognosis and diagnosis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for cancer prognosis and diagnosis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1700624