Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or... – The polynucleotide encodes an inhibitory rna molecule
Patent
1997-07-30
2000-01-04
Smith, Lynette R. F.
Multicellular living organisms and unmodified parts thereof and
Method of introducing a polynucleotide molecule into or...
The polynucleotide encodes an inhibitory rna molecule
435468, 435410, 435419, 536 236, 800278, 800286, 800290, 800295, 800298, 800306, C12N 504, C12N 1529, C12N 1562, A01H 500
Patent
active
06011200&
ABSTRACT:
The present invention is based on the unexpected observation that DNA methylation, particularly at cytosine residues, regulates the rate of development of a plant. Based on this observation, the present invention provides methods of increasing or decreasing the rate of development of a plant by either increasing or decreasing the amount of methylated DNA found in the plant. The present invention further provides plants that have been altered such that their rate of maturation is either increased or decreased relative to the rate of maturation of a non-altered plant.
REFERENCES:
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Finnegan, E.J. et al.: "Isolation and Identification by Sequence Homology of a Putative Cytosine Methyltransferase from Arabidopsis Thaliana" Nucleic Acid Research, vol. 21, No. 10, 1993, pp. 2383-2388.
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Finnegan, E.J. et al.: "Reduced DNA Methylation in Arabidopsis Thaliana Results in Abnormal Plant Development" Proceedings of the National Academy of Sciences of the USA, vol. 93, Aug. 1996, pp. 8449-8454.
Richards, E.J., et al.: "DNA Methylation and Plant Development" Trends in Genetics, vol. 13, No. 8, Aug. 1997, pp. 319-323.
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Chen Jychian
Dellaporta Stephen L.
Smith Lynette R. F.
Yale University
Zaghmout Ousama
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