Methods, devices, kits and compositions for detecting whipworm

Details Methods, devices, kits and compositions for detecting whipworm Methods, devices, kits and compositions for detecting whipworm

2011-08-09

2011-08-09

Nickol, Gary (Department: 1645)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007100

Reexamination Certificate

active

07993861

ABSTRACT:
Methods, devices, kits and compositions for detecting the presence or absence of whipworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of whipworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, roundworm, and heartworm. Confirmation of the presence or absence of whipworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.

REFERENCES:
patent: 4322495 (1982-03-01), Kato
patent: 4756908 (1988-07-01), Lew
patent: 4789631 (1988-12-01), Maggio
patent: 4839275 (1989-06-01), Weil
patent: 4978504 (1990-12-01), Nason
patent: 5078968 (1992-01-01), Nason
patent: 5238649 (1993-08-01), Nason
patent: 5266266 (1993-11-01), Nason
patent: 5726010 (1998-03-01), Clark
patent: 5753787 (1998-05-01), Hawdon et al.
patent: 5843706 (1998-12-01), Cobon et al.
patent: 5882943 (1999-03-01), Aldeen
patent: 6057166 (2000-05-01), Childs et al.
patent: 6391569 (2002-05-01), Grieve et al.
patent: 6596502 (2003-07-01), Lee
patent: 7303752 (2007-12-01), Hotez et al.
patent: 2002/0132270 (2002-09-01), Lee
patent: 2003/0129680 (2003-07-01), O'Connor
patent: 2004/0014087 (2004-01-01), Hodgson et al.
patent: 2004/0214244 (2004-10-01), Tonelli et al.
patent: 2005/0042232 (2005-02-01), Hotez et al.
patent: 2006/0198844 (2006-09-01), Langenfeld
patent: 2007/0053920 (2007-03-01), Heath et al.
patent: 2008/0033148 (2008-02-01), Xu et al.
patent: 2008/0108793 (2008-05-01), Berman et al.
patent: 2008/0311557 (2008-12-01), Elsemore et al.
patent: 2008/0311600 (2008-12-01), Elsemore et al.
patent: 2009/0286228 (2009-11-01), Elsemore et al.
patent: 2009/0286229 (2009-11-01), Elsemore et al.
patent: 2009/0286230 (2009-11-01), Elsemore et al.
patent: 2009/0286231 (2009-11-01), Elsemore et al.
patent: WO 98/12563 (1998-03-01), None
patent: WO 02/075313 (2002-09-01), None
patent: WO 2003/032917 (2003-04-01), None
patent: WO 2004/097412 (2004-11-01), None
patent: WO 2006/135799 (2006-12-01), None
patent: WO 2008/156650 (2008-12-01), None
patent: WO 2009/143080 (2009-11-01), None
patent: WO 2009/143083 (2009-11-01), None
Drake et al 1994 Proc. R. Soc. B 257:255-261.
Houghten et al. (Vaccines, 1986, Edited by Fred Brown: Cold Spring Harbor Laboratory).
Holmes, Exp. Opin.lnvest. Drugs, 2001, 10(3):511-519).
Greenspan et al (Nature Biotechnology, 1999, 7:936-937).
NCBI Blast: SEQ ID No. 4 (Performed Aug. 27, 2009 using http://blast.ncbi.nlm.nih.gov/blast.cgi).
Bailey, “The Raising of a Polyclonal Antiserum to a Protein”,Methods Mol. Biol., vol. 32, pp. 381-388, (1994).
Barker, et al., “Isolation of a gene family that encodes the porin-like proteins from the human parasitic nematodeTrichuris trichiura”, Gene, vol. 229, pp. 131-136, (1999).
Dean, “Preparation and Characterization of Monoclonal Antibodies to Proteins and Other Cellular Components”,Methods Mol. Biol., vol. 32, pp. 361-379, (1994).
Dean, “Preparation and Testing of Monoclonal Antibodies to Recombinant Proteins”,Methods Mol. Biol., vol. 80, pp. 23-37, (1998).
Drenckhanhn, et al., “Production of Polyclonal Antibodies against Proteins and Peptides”,Methods Cell Biol., vol. 37, pp. 7-56, (1993).
Dryden, et al., “Comparison of Common Fecal Flotation Techniques for the Recovery of Parasite Eggs and Oocysts”,Vet. Ther., vol. 6, No. 1, pp. 15-28, (2005).
Gullick, “Production of Antisera to Synthetic Peptides”,Methods Mol. Biol., vol. 32. pp. 389-399, (1994).
Kennedy, “The Nematode Polyprotein Allergens/Antigens”,Parasitol. Today, vol. 16, No. 9, pp. 373-380, (2000).
Memoranda, “Parasite Antigens”,Bull. World Health Organ, vol. 52, pp. 237-249, (1975).
Morrison, “In Vitro Antibodies: Strategies for Production and Application”,Annu. Rev. Immunol., vol. 10, pp. 239-265, (1992).
Prociv et al., “Human enteric infection withAncyostoma caninum: hookworms reappraised in the light of a “new” zoonosis”,Acta. Tropica., vol. 62, pp. 23-44, (1996).
Wright, et al., “Genetically Engineered Antibodies: Progress and Prospects”,Crit. Rev. Immunol., vol. 12 (3-4), pp. 125-168, (1992).
Xia, et al., “The ABA-1 allergen ofAscaris lumbricoides: sequence polymorphism stage and tissue-specific expression, lipid binding function and protein biophysical properties”,Parasitology, vol. 120 (Pt.2), pp. 211-224, (2000).
Yahiro, et al., “Identification, characterization and expression ofToxocara canisnematode polyprotein allergen TBA-1”,Parasite Immunol., vol. 20, No. 8, pp. 351-357, (1998).
Uniprot Submission P91811. May 1997 [Retrieved from the internet Nov. 7, 2009: [URL:http://www.uniprot.org/uniprot/P91811].
Uniport submission O44397. Jun. 1988 [Retrieved from the internet Nov. 11, 2009: [<URL:http://www.uniport.org/uniport/O44397>].
Babin, et al., “The Isoinhibitors of Chymotrypsin/Elastase fromAscaris lumbricoides: The Primary Structure”,Archives of Biochemistry and Biophysics, vol. 232, No. 1, pp. 143-161, (1984).
Cappello, et al., “Ancylostoma caninumanticoagulant peptide: A hookworm-derived inhibitor of human coagulation factor Xa”,Proc. Natl. Acad. Sci., vol. 92, pp. 6152-1656, (1995).
Ford, et al., “Characterization of a Novel Filarial Serine Protease Inhibitor,Ov-SPI-1, fromOnchocerca volvulus, with Potential Multifunctional Roles during Development of the Parasite”,J. of Biol. Chem., vol. 280, No. 49, pp. 40845-40856, (2005).
Fraefel, et al., “The amino acid sequence of a trypsin inhibitor isolated fromAscaris(Ascaris lumbricoidesvar.suum)”,Biochim. Biophys. Acta, vol. 154, pp. 615-617, (1968).
Goodman, et al., “Isolation of the Trypsin Inhibitors inAscaris lumbricoidesvar.suumUsing Affinity Chromatography”,Analytical Biochemistry, vol. 120, pp. 387-393 (1982).
Grasberger, et al., “High-resolution structure ofAscaristrypsin inhibitor in solution: direct evidence for a pH-induced conformational transition in the reactive site”,Structure, vol. 2, No. 7, pp. 669-678, (1994).
Gronenborn, et al., “Sequential resonance assignment and secondary structure determination of theAscaristrypsin inhibitor, a member of a novel class of proteinase inhibitors”,Biochemistry, vol. 29, No. 1, pp. 183-189, (1990).
Harrison, et al., “Molecular Characterization ofAncylostomaInhibitors of Coagulation Factor Xa”,J. of Biol. Chem., vol. 277, No. 8, pp. 6223-6229, (2002).
Hawley, et al., “Ascaris suum: Are Trypsin Inhibitors Involved in Species Specificity of Ascarid Nematodes?”,Experimental Parasitology, vol. 75, pp. 112-118 (1992).
Huang, et al., “The molecular structure of the complex ofAscarischymotrypsin/elastase inhibitor with porcine elastase”,Structure, vol. 2, No. 7, pp. 679-689, (1994).
Lu, et al., “Anisakis simplex: Mutational Bursts in the Reactive Site Centers of Serine Protease Inhibitors from an Ascarid Nematode”,Experimental Parasitology, vol. 89, pp. 257-261, (1998).
Martzen, et al., “Ascaris suum: Localization by Immunochemical and Fluorescent Probes of Host Proteases and Parasite Proteinase Inhibitors in Cross-sections”,Experimental Parasitology, vol. 60, pp. 139-149, (1985).
Nguyen, et al., “Expression and characterization of elastase inhibitors from the ascarid nematodesAnisakis simplexandAscaris suum”, Mol. Biochem. Parasitology, vol. 102, pp. 79-89, (1999).
Peanasky, et al., “The Isoinhibitors of Chymotrypsin/Elastase fromAscaris lumbricoides: Isolation by Affinity Chromatography and Association with the Enzymes”,Archives of Biochemistry and Biophysics, vol. 232, No. 1, pp. 127-134, (1984).
Rhoads, et al., “Trichuris suis: A Secretory Serine Protease Inhibito

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