Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2005-02-15
2005-02-15
Berman, Jack I. (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C436S180000, C422S105000, C422S063000, C435S030000, C073S864000, C073S864810
Reexamination Certificate
active
06855925
ABSTRACT:
Provided is a method for preparing a sample surface for analysis that involves placing a sample surface in droplet-receiving relationship to a reservoir containing an analysis-enhancing fluid. Typically, the analysis-enhancing fluid is comprised of a mass spectrometry matrix material and a carrier fluid, and the carrier fluid is comprised of a low volatility solvent. A droplet of the analysis-enhancing fluid from the reservoir such that the droplet is deposited on the sample surface at a designated site. Such ejection is typically, but not necessarily carried out through the application of focused acoustic energy. Then, the sample is subjected to conditions sufficient to allow the analysis-enhancing fluid to interact with the sample surface to render the sample surface suitable for analysis. Optionally, the sample is analyzed at the selected site. Also provided are systems and devices for preparing a sample surface for analysis.
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Caprioli Richard Michael
Ellson Richard N.
Mutz Mitchell W.
Berman Jack I.
Picoliter Inc.
Reed Dianne E.
Reed Intellectual Property Law Group
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