Methods designing multiple mRNA transcript nucleic acid...

Details Methods designing multiple mRNA transcript nucleic acid... Methods designing multiple mRNA transcript nucleic acid...

2006-04-18

2006-04-18

Martinell, James (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091100, C702S020000, C536S024300

Reexamination Certificate

active

07029854

ABSTRACT:
Methods of identifying a sequence of a nucleic acid that is suitable for use as a surface immobilized probe for two or more mRNA transcripts encoded by the same gene are provided. In practicing the subject methods, a consensus region for the two or more transcripts is first identified, and this identified consensus region is then employed to identify the suitable nucleic acid sequence, e.g., by using a probe design protocol. The subject invention also includes algorithms for performing the subject methods recorded on a computer readable medium, as well as computational analysis systems that include the same. Also provided are nucleic acid arrays produced with probes having sequences identified by the subject methods, as well as methods for using the same.

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patent: 6162601 (2000-12-01), Bandman et al.
patent: 6251588 (2001-06-01), Shannon et al.
Divoky et al, Gene 247(1-2), 111 (2000).

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