Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2005-05-17
2005-05-17
Housel, James (Department: 1648)
Chemistry: molecular biology and microbiology
Vector, per se
C435S091100, C435S091330, C435S091400, C435S094000, C435S091420, C530S300000, C514S024000
Reexamination Certificate
active
06893865
ABSTRACT:
Isolated recombinant polynucleotides comprising elements which promote encapsidation into AAV particles, packaging cells comprising the recombinant polynucleotides, and methods for their use are provided in the present invention. These isolated recombinant polynucleotides comprise a non-AAV ITR encapsidation element (such as the P1 sequence located within the AAV S1 integration site of human chromosome 19) operably linked to one or more heterologous genes to be encapsidated. The constructs may be either integrated into a mammalian cell genome, maintained episomally, or provided transiently.
REFERENCES:
patent: 5139941 (1992-08-01), Muzyczka et al.
patent: 5173414 (1992-12-01), Lebkowski et al.
patent: 5354678 (1994-10-01), Lebkowski et al.
patent: 5580703 (1996-12-01), Kotin et al.
patent: 5587308 (1996-12-01), Carter et al.
patent: 5652224 (1997-07-01), Wilson et al.
patent: 5658776 (1997-08-01), Flotte et al.
patent: 5658785 (1997-08-01), Johnson
patent: 5756283 (1998-05-01), Wilson et al.
patent: 5786211 (1998-07-01), Johnson
patent: 5837484 (1998-11-01), Trempe et al.
patent: 5843742 (1998-12-01), Natsoulis et al.
patent: 5846528 (1998-12-01), Podsakoff et al.
patent: 5856152 (1999-01-01), Wilson et al.
patent: 5858351 (1999-01-01), Podsakoff et al.
patent: 5858775 (1999-01-01), Johnson
patent: 5866552 (1999-02-01), Wilson et al.
patent: 5866696 (1999-02-01), Carter et al.
patent: 5869305 (1999-02-01), Samulski et al.
patent: 5871982 (1999-02-01), Wilson et al.
patent: 5872154 (1999-02-01), Wilson et al.
patent: 5989540 (1999-11-01), Carter et al.
patent: 5990279 (1999-11-01), Carter et al.
patent: 6165781 (2000-12-01), Carter et al.
patent: 6174527 (2001-01-01), Wilson et al.
patent: 6211160 (2001-04-01), Wilson et al.
patent: 6251677 (2001-06-01), Wilson et al.
patent: 6251957 (2001-06-01), Wilson et al.
patent: 6258595 (2001-07-01), Gao et al.
patent: 6261551 (2001-07-01), Wilson et al.
patent: 6270996 (2001-08-01), Wilson et al.
patent: 6274354 (2001-08-01), Wilson et al.
patent: 6281010 (2001-08-01), Gao et al.
patent: 6346415 (2002-02-01), Feldhaus
patent: 6372208 (2002-04-01), Wilson et al.
patent: 6387368 (2002-05-01), Wilson et al.
patent: 6399385 (2002-06-01), Croyle et al.
patent: 6436392 (2002-08-01), Engelhardt et al.
patent: 6475769 (2002-11-01), Wilson et al.
patent: 6482634 (2002-11-01), Wilson et al.
patent: 6485966 (2002-11-01), Gao et al.
patent: 6537540 (2003-03-01), Burstein et al.
patent: 6541258 (2003-04-01), Allen et al.
patent: 6566118 (2003-05-01), Atkinson et al.
patent: 6596535 (2003-07-01), Carter
patent: 6642051 (2003-11-01), Lynch et al.
patent: 6759237 (2004-07-01), Wilson et al.
patent: 20010006955 (2001-07-01), Wilson et al.
patent: 20020001581 (2002-01-01), Lynch et al.
patent: 20020037867 (2002-03-01), Wilson et al.
patent: 20020127582 (2002-09-01), Atkinson et al.
patent: 20020131956 (2002-09-01), Walsh et al.
patent: 20020160501 (2002-10-01), Atkinson et al.
patent: 20020164783 (2002-11-01), Feldhaus
patent: 20020182182 (2002-12-01), Wilson et al.
patent: 20020197237 (2002-12-01), Engelhardt et al.
patent: 20030040101 (2003-02-01), Wilson et al.
patent: 20030073232 (2003-04-01), Wilson et al.
patent: 20030082145 (2003-05-01), Johnson
patent: 20030103939 (2003-06-01), Engelhardt et al.
patent: 20030103942 (2003-06-01), Burstein et al.
patent: 20030113295 (2003-06-01), Burstein et al.
patent: 20030119191 (2003-06-01), Gao et al.
patent: 20030175974 (2003-09-01), Allen
patent: 20030219735 (2003-11-01), Carter
patent: 20040052764 (2004-03-01), Hildinger et al.
patent: 20040057931 (2004-03-01), Wilson et al.
patent: 20040057932 (2004-03-01), Wilson et al.
patent: 20040057933 (2004-03-01), Wilson et al.
patent: 20040062752 (2004-04-01), Walsh et al.
patent: 0 488 528 (1992-06-01), None
patent: WO 9208796 (1992-05-01), None
patent: WO 9324641 (1993-12-01), None
patent: WO 9413788 (1994-06-01), None
patent: WO 9428143 (1994-12-01), None
patent: WO 9506743 (1995-03-01), None
patent: WO 9513365 (1995-05-01), None
patent: WO 9513392 (1995-05-01), None
patent: WO 9514771 (1995-06-01), None
patent: WO 9520671 (1995-08-01), None
patent: WO 9534670 (1995-12-01), None
patent: WO 9600587 (1996-01-01), None
patent: WO 9613598 (1996-05-01), None
patent: WO 9617947 (1996-06-01), None
patent: WO 9626285 (1996-08-01), None
patent: WO 9626286 (1996-08-01), None
patent: WO 9639530 (1996-12-01), None
patent: WO 9709441 (1997-03-01), None
patent: WO 9709442 (1997-03-01), None
patent: WO 9732990 (1997-09-01), None
patent: WO 9809656 (1998-03-01), None
patent: WO 9809657 (1998-03-01), None
patent: WO 9810086 (1998-03-01), None
patent: WO 9810088 (1998-03-01), None
patent: WO 9827204 (1998-06-01), None
patent: WO 9827207 (1998-06-01), None
patent: WO 9911764 (1999-03-01), None
patent: WO 9914351 (1999-03-01), None
patent: WO 9915677 (1999-04-01), None
patent: WO 9915685 (1999-04-01), None
patent: WO 9920773 (1999-04-01), None
patent: WO 9920779 (1999-04-01), None
patent: WO 9947691 (1999-09-01), None
patent: WO 9960146 (1999-11-01), None
patent: WO 0014205 (2000-03-01), None
patent: WO 0028061 (2000-05-01), None
patent: WO 0053788 (2000-09-01), None
patent: WO 0055342 (2000-09-01), None
patent: WO 0065038 (2000-11-01), None
patent: WO 0073480 (2000-12-01), None
patent: WO 0073481 (2000-12-01), None
patent: WO 0075353 (2000-12-01), None
patent: WO 0075365 (2000-12-01), None
patent: WO 0111034 (2001-02-01), None
patent: WO 0123001 (2001-04-01), None
patent: WO 0125462 (2001-04-01), None
patent: WO 0125465 (2001-04-01), None
patent: WO 0127303 (2001-04-01), None
patent: WO 0183692 (2001-11-01), None
patent: WO 0183730 (2001-11-01), None
patent: WO 03006616 (2003-01-01), None
patent: PCTUS2004/009950 (2004-03-01), None
patent: PCTUS2004/010045 (2004-03-01), None
Merriam Webster's Collegiate Dictionary Tehth Edition, p. 823 and 108.*
Chiorini et al. Human Gene Ther. 1995, vol. 6, pp. 1531-1541.*
Salvetti, A. et al. (1998) “Factors Influencing Recombinant Adeno-Associated Virus Production,”Human Gene Therapy9(5):695-706.
Zhou, X. and Muzyczka, N. (1998). “In Vitro Packaging of Adeno-Associated Virus DNA,”Journal of Virology72(4):3241-3247.
U.S. Appl. No. 09/578,561, Rasty et al., filed May 25, 2000.
U.S. Appl. No. 09/665,852, Wilson et al., filed Sep. 20, 2000.
U.S. Appl. No. 09/684,554, Engelhardt et al., filed Oct. 6, 2000.
U.S. Appl. No. 09/689,136, Engelhardt et al., filed Oct. 12, 2000.
U.S. Appl. No. 09/689,430, Walsh et al., filed Oct. 12, 2000.
U.S. Appl. No. 10/089,394, Chen et al., filed Mar. 29, 2002.
U.S. Appl. No. 10/375,777, Johnson, filed Feb. 26, 2003.
U.S. Appl. No. 10/615,119, Lynch et al., filed Jul. 7, 2003.
U.S. Appl. No. 10/815,262, Engelhardt et al., filed Mar. 31, 2004.
U.S. Appl. No. 10/815,557, Engelhardt et al., filed Mar. 31, 2004.
U.S. Appl. No. 10/837,029, Engelhardt et al., filed Apr. 30, 2004.
Flotte, T.R. et al. (1995). “An Improved System for Packaging Recombinant Adeno-Associated Virus Vectors Capable of In Vivo Transduction,”Gene Ther.2:29-37.
Giraud, C. et al. (1995). “Recombinant Junctions Formed by Site-Specific Integration of Adeno-Associated Virus into an Episome,”J. Virol.69(11):6917-6924.
Giraud, C. et al. (1994). “Site-Specific Integration by Adeno-Associated Virus is Directed by a Cellular DNA Sequence,”Proc. Natl. Acad. Sci. USA91:10039-10043.
Linden, R.M. et al. (1996). “Site-Specific Integration by Adeno-Associated Virus,”Proc. Natl. Acad. Sci. USA93:11288-11294.
Samulski, R.J. et al. (1989). “Helper-Free Stocks of Recombinant Adeno-Associated Viruses: Normal Integration does Not Require Viral Gene Expression,”J. Virol.63(9):3822-3828.
Srivastiva, C.H. et al. (1989). “Construction of a Recombinant Human Parvovirus B19: Adeno-Associated VIrus 2 (AAV) DNA Inverted Terminal Repeats are Functional in an AAV-B19 Hybrid Virus,”Proc. Natl. Acad. Sci. USA86:8078-8082.
Tratschin, J.-D. et al. (1984). “A Human Parvovirus, Adeno-Associated Virus, as a Eucaryotic Vector: Transient Expression and Encapsidation of the
Burstein Haim
Lockert Dara H.
Lynch Carmel M.
Stephan Anthony M.
Housel James
Li Bao Qun
Morrison & Foerster
Targeted Genetics Corporation
LandOfFree
Methods, compositions, and cells for encapsidating... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods, compositions, and cells for encapsidating..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods, compositions, and cells for encapsidating... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3431163