Methods and tools for detecting collagen degradation

Details Methods and tools for detecting collagen degradation Methods and tools for detecting collagen degradation

2008-07-29

2008-07-29

Davis, Ruth A (Department: 1651)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C435S325000

Reexamination Certificate

active

10840653

ABSTRACT:
Fluorophore-labeled collagen covalently bound to a cell culture vessel can be used to assay collagen degradation by a variety of cell types, including osteoclasts and tumor cells. Such assays provide a high throughput platform for rapid screening of large numbers of potential modulators of, for example, tumor metastasis or osteoclast differentiation and/or function.

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