Methods and test kits for specific and sensitive diagnosing of p

Details Methods and test kits for specific and sensitive diagnosing of p Methods and test kits for specific and sensitive diagnosing of p

1995-06-07

1998-04-07

Huff, Sheela

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 732, 435 74, 435 79, 435 792, 435810, 435325, 435326, 435338, 435975, 435974, 436501, 436518, 436524, 436523, 436533, 436528, 436534, 436819, 436808, 436909, 5303871, 5303881, 53038826, 5303911, 5303891, 422101, G01N 3353, G01N 33537, G01N 33543, G01N 33554, G01N 33551, G01N 33546, C07K 1600, C12P 2108

Patent

active

057363412

ABSTRACT:
Methods and test kits are described which provide a reliable, sensitive and selective assessment of periodontal disease activity, peri-implantitis or HIV(+)-infection/AIDS-disease related periodontal diseases. The preferred methods and test kits are constructed to be easy and rapid chair-side tests. The method is based on the preparation and use of monoclonal antibodies which recognize the active mammalian matrix metalloproteinase-S (MMP-8) and is capable of differentiating between said active matrix metalloproteinase-8 and its inactive proform.

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