Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2011-05-03
2011-05-03
Nguyen, Kiet T (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C250S282000
Reexamination Certificate
active
07935921
ABSTRACT:
Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS and 2D-LC-MS/MS) for the analysis of endogenous biomarkers, including steroid hormones, such as estrone and estradiol, thyroid hormones, such as free thyroxine, and metabolites, such as 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3, in biological samples.
REFERENCES:
patent: 5447553 (1995-09-01), Apffel, Jr. et al.
patent: 5772874 (1998-06-01), Quinn et al.
patent: 5795469 (1998-08-01), Quinn et al.
patent: 5919368 (1999-07-01), Quinn et al.
patent: 5968367 (1999-10-01), Quinn et al.
patent: 6107623 (2000-08-01), Bateman et al.
patent: 6124137 (2000-09-01), Hutchens et al.
patent: 6204500 (2001-03-01), Whitehouse et al.
patent: 6339218 (2002-01-01), Kato et al.
patent: 6410913 (2002-06-01), Brekenfeld et al.
patent: 6437327 (2002-08-01), Takada et al.
patent: 6541263 (2003-04-01), Gao
patent: 6635173 (2003-10-01), Brann
patent: 6808635 (2004-10-01), Brann
patent: 7452678 (2008-11-01), Durham et al.
patent: 2002/0084222 (2002-07-01), Brann
patent: 2003/0015019 (2003-01-01), O'Brien
patent: 2004/0235188 (2004-11-01), Soldin
patent: 2004/0235193 (2004-11-01), Soldin
patent: 2005/0161399 (2005-07-01), Dillon et al.
patent: WO 03/089921 (2003-10-01), None
patent: WO 2004/090525 (2004-10-01), None
patent: WO 2004/090553 (2004-10-01), None
Anari, M. et al., Derivation of ethinylestradiol with dansyl chloride to enhance electrospray ionization: application in trace analysis of ethinylestradiol in rhesus monkey plasma, Anal. Chem., vol. 74, No. 16, pp. 4136-4144, 2002.
Budzinski, H. et al., Analysis of hormonal steroids in fish plasma and bile by coupling solid-phase extraction to gc/ms, Anal. Bioanal. Chem., vol. 386, pp. 1429-1439, 2006.
Draisci, R. et al., Quantification of 17 β-estradiol residues n bovine serum by liquid chromatography-tandem mass spectrometry with atmospheric pressure chemical ionization, p. 2605-2609, 1998.
Dugo, P. et al., Comprehensive Tow Dimensional Normal Phase (Adsorption)-Reversed-Phase Liquid Chromatography, Anal. Chem., vol. 76, No. 9, pp. 2525-2530, 2004.
Fedeniuk, R. et al., Validaiotn of a gas chromatography mass spectrometry method for the determination of pg/ml levels of 17 β-estradiol and 17 β-trenbolone in bovine serum, J. Chromatogr B. Analyt Technol Biomed Life Sci., vol. 802, No. 2, pp. 307-315, 2004.
Ferretti, G. et al., Simultaneous analysis of 17 {acute over (α)}-estradiol and 17β-estradiol in bovine serum by liquid chromatography-tandem mass spectrometry, Journal of Chromatography B, vol. 871, pp. 135-140, 2008.
Guo, T. et al., Steroid profiles using liquid chromatography-tandem mass spectrometry with atmospheric pressure photoionization source, Arch. Pathol. Lab. Med., vol. 128, No. 4, pp. 469-475, 2004.
Higashi, T. et al., Procedure for increasing the detection responses of estrogens in lc-ms based on introduction of a nitrobenzene moiety followed by electron capture atmospheric pressure chemical ionization, Anal. Bioanal. Chem., vol. 386, pp. 658-665, 2006.
Jandera, P. et al., Two-dimensional liquid chromatography normal-phase and reversed-phase separation of (co)oligomers, Journal of Chromatography A, vol. 1119, pp. 3-10, 2006.
Kawaguchi, M. et al., Dual derivatization-stir bar sorptive extraction-thermal desorption-gas chromatography-mass spectrometry for determination of 17β-estradiol in water sample, Journal of Chromatography A, vol. 1105, pp. 140-147, 2006.
Nelson, R. et al., Liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of estradiol and estrone in human plasma, Clinical Chemistry, vol. 50, No. 2, pp. 373-384, 2004.
Tai, S. et al., Development and evaluation of a reference measurement procedure for the determination of estradiol-17β in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry, Anal. Chem., vol. 77, No. 19, pp. 6359-6363, 2005.
Xu, X. et al., Measuring fifteen endogenous estrogens simultaneously in human urine by high-performance liquid chromatography-mass spectrometry, Anal. Chem., vol. 77, No. 20, pp. 6646-6654, 2005.
Zacharia, L. et al., A gas chromatography/mass spectrometry assay to measure estradiol, catecholestradiols, and methoxyestradiols in plasma, Steroids, vol. 69, pp. 255-261, 2004.
Zhang, H. et al., Quantitative and qualitative determination of estrogen sulfates in human urine by liquid chromatography/tandem mass spectrometry using 96-well technology, Anal. Chem., vol. 71, No. 18, pp. 3955-3964, 1999.
Lagana et al., “Liquid chromatography tandem mass spectrometry applied to the analysis of natural and synthetic steroids in environmental waters,”Analytical Letters, 2001, 34(6): 913-926.
Monnoyer et al., “Development of a high-performance liquid chromatography-tandem mass spectrometry method for the determination of flurogestone acetate in ovine plasma,”Journal of Chromatography B: Biomedicial Sciences&Applications, 2005, 819(2): 245-251.
Robb et al., “Atmospheric pressure photoionization: an ionization method for liquid chromatography-mass spectrometry,”Anal. Chem., 2000, 72(15): 3653-3659.
Zimmer et al., “Comparison of turbulent-flow chromatography with automated solid-phase extraction in 96-well plates and liquid-liquid extraction used as plasma sample preparation techniques for liquid chromatography-tandem mass spectrometry,”J. Chromatogr. A., 1999, 854: 23-35.
Yost,Tandem Mass Spectrometry, Chapter 8, Ed. McLafferty, John Wiley and Sons: 1983, 175-195.
International Search Report for Patent Cooperation Treaty Application Serial No. PCT/US2007/012525 mailed Jul. 2, 2008.
Written Opinion of the International Searching Authority for Patent Cooperation Treaty Application Serial No. PCT/US2007/012525 mailed Jul. 2, 2008.
de Alda, M. et al., Liquid chromatography-(tandem) mass spectrometry of selected emerging pollutants (steroid sex hormones, drugs and alkylphenolic surfactants) in the aquatic environment, Journal of Chromatography A, vol. 1000, pp. 503-526, 2003.
Antignac, J. et al., Collision-induced dissociation of corticosteroids in electrospray tandem mass spectometry and development of a screening method by high performance liquid chromatography/tandem mass spectrometry, Rapid communications in Mass Spectrometry, vol. 14, pp. 33-39, 2000.
Asperger, A. et al., Trace determination of priority pesticides in water by means of high-speed on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry using turbulent-flow chromatography colums for enrichment and a short monolithic column for fast liquid chromatographic separation, Journal of Chromatography A, vol. 960, pp. 109-119, 2002.
Ayrton, J. et al., Ultra-high flow rate capillary liquid chromatography with Mass Spectrometric detection for the direct analysis of pharmaceuticals in plasma at sub-nanogram per millilitre concentrations, Rapid Communications in Mass Spectrometry, vol. 13, pp. 1657-1662, 1999.
Carignan, G. et al., High-performance liquid chromatographic analysis of estradiol valerate-testosterone enanthate in oily formulations, Journal of Chromatography, vol. 301, pp. 292-296, 1984.
Chang, Y. et al., Quantitative measurement of male steroid hormones using automated on-line solid phase extraction-liquid chromatography-tandem mass spectrometry and comparison with radioimmunoassay, Analyst, vol. 128, pp. 363-368, 2003.
Choi, M. et al., Rapid HPLC-electrospray tadem mass spectrometric assay for urinary testosterone and dihydrotestosterone glucuronides from patients with benign prostate hyperplasia, Clinical Chemistry, vol. 49, No. 2, pp. 322-325, 2003.
Choi, M. et al., Determination of four anabolic steroid metabolites by gas chromatography/mass spectrometry with negative ion chemical ionization and tandem mass spectrometry, Rapid Communications in Mass Spectrometry, vol. 12, pp. 1949-1755, 1998.
Dorgan, J. et al., Measurement of steroid sex hormones in serum, a comparison of radioimmunoassay and mass spectrometry, Steroids, vol. 67, pp. 151-158, 2002.
Draisci, R. et al.,
Grant Russell Philip
Morr Mary Katherine
Patel Milan Rameshkumar
Wagner Andrew Dennis
Kilpatrick Townsend & Stockton LLP
Laboratory Corporation of America Holdings
Nguyen Kiet T
LandOfFree
Methods and systems for the quantitative analysis of biomarkers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and systems for the quantitative analysis of biomarkers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and systems for the quantitative analysis of biomarkers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2657767