Chemistry: analytical and immunological testing – Including chromatography
Reexamination Certificate
2009-09-02
2011-11-29
Mui, Christine T (Department: 1774)
Chemistry: analytical and immunological testing
Including chromatography
C250S282000, C250S281000
Reexamination Certificate
active
08067243
ABSTRACT:
Methods and systems for assessing patient compliance with opioid drug therapy are provided. A liquid chromatography tandem mass spectrometer (LC/MS/MS) can be used to simultaneously detect a set of measurements including an amount of at least ten opioids (and their metabolites) in a body fluids sample from a patient. The set of at least ten opioids can include at least oxymorphone and fentanyl. The amounts of opioids and their metabolites are analyzed. For example, the ratios of opioids and their respective metabolites can be used to determine which opioids a patient has been administered. A report of patient compliance is generated based on the set of measurements.
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Coles et al., Simultaneous Determination of Codeine, Morphine, Hydrocodone, Hydromorphone, Oxycodone, and 6-Acetylmorphine in Urine, Serum, Plasma, Whole Blood, and Meconium by LC-MS-MS; Journal of Analytical Toxicology, vol. 31, Jan./Feb. 2007.
Beardsley Grant D.
Erfurth Stephen C.
Mui Christine T
Myers Bigel & Sibley & Sajovec
Oregon Medical Laboratories
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