Methods and reagents for treating glucose metabolic disorders

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S375000, C530S307000, C530S324000

Reexamination Certificate

active

07745216

ABSTRACT:
The invention relates to methods for potentiating, enhancing or restoring glucose responsivity in pancreatic islets or cells. The methods can be used as therapies for diseases caused by, or coincident with, aberrant glucose metabolism, such as Type II Diabetes Mellitus.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4839343 (1989-06-01), Waeber et al.
patent: 4891357 (1990-01-01), Kalra
patent: 4892538 (1990-01-01), Aebischer et al.
patent: 5423872 (1995-06-01), Cigaina et al.
patent: 5459039 (1995-10-01), Modrich et al.
patent: 5498531 (1996-03-01), Jarrell
patent: 5545549 (1996-08-01), Gerald et al.
patent: 5574010 (1996-11-01), McFadden
patent: 5604203 (1997-02-01), Balasubramaniam
patent: 5696093 (1997-12-01), Tseng et al.
patent: 5912227 (1999-06-01), Croom et al.
patent: 5916869 (1999-06-01), Croom, Jr. et al.
patent: 5939462 (1999-08-01), Connell et al.
patent: 5968819 (1999-10-01), Gerald et al.
patent: 5980945 (1999-11-01), Ruiz
patent: 5989920 (1999-11-01), Gerald et al.
patent: 6013622 (2000-01-01), Bruno et al.
patent: 6391343 (2002-05-01), Yen
patent: 6558708 (2003-05-01), Lin
patent: 6569832 (2003-05-01), Knudsen et al.
patent: 7396809 (2008-07-01), Lu et al.
patent: 2002/0094346 (2002-07-01), Lin
patent: 2003/0224983 (2003-12-01), Nielsen
patent: 2004/0228846 (2004-11-01), Pang et al.
patent: 2009/0082309 (2009-03-01), Bachovchin et al.
patent: 0 992 239 (2003-03-01), None
patent: WO 89/01967 (1989-03-01), None
patent: WO 90/02580 (1990-03-01), None
patent: WO 90/15637 (1990-12-01), None
patent: WO 91/10425 (1991-07-01), None
patent: WO 91/10470 (1991-07-01), None
patent: WO-9116917 (1991-11-01), None
patent: WO 94/16101 (1994-07-01), None
patent: WO-9517906 (1995-07-01), None
patent: WO-9616542 (1996-06-01), None
patent: WO-99/15516 (1999-04-01), None
patent: WO-00/47219 (2000-08-01), None
patent: WO-00/47219 (2000-08-01), None
patent: WO-00/68197 (2000-11-01), None
patent: WO-01/62737 (2001-08-01), None
patent: WO-01/76631 (2001-10-01), None
patent: WO-03/026591 (2003-04-01), None
Voisin et al. Peptide YY receptors in the proximal tubule PKSV-PCT cell line derived from transgenic mice. The Journal of Biological Chemistry. vol. 268/27 pp. 20547-20554 (1993).
Slack et al. Developmental biology of the pancreas. Development vol. 121 pp. 1569-1580 (1995).
Karlsson et al., A role for islet peptide YY in the regulation of insulin secretion. Acta Physil. Scand vol. 157 pp. 305-306 (1996).
Tito et al., Peptide YY ameliorates cerulein-induced pancreatic injury in the rat. American Journal of Surgery vol. 165/6 pp. 690-696 (1993).
Wells, Additivity of mutational effects in proteins. Biochemistry 29:8509-8517 (1990).
Towfigh et al. Peptide YY exhibits mitogenic effect on pancreatic ductal cells while improving acute pancreatitis. Surgical Forum vol. 50:25-27 (1999).
Bertrand et al. Evidence for a direct inhibitory effect of PYY on insulin secretion in rats. Pancreas 7(5):595-600 (1992).
Bickel eta l. Neonatal mass screening for metabolic disorders. Summary of recent sessions of the committee of experts to study inborn metabolic diseases, public health committee, Council of Europe. European Journal of Pediatric 137:133-139 (1981).
Ramo et al. Neuropeptide Y and peptide YY stimulate the growth of exocrine pancreatic carcinoma cells. Neuropeptides Feb; 15(2):101-6 (1990).
Mulder et al. Expression of Non-classical islet hormone-like peptides during the embryonic development of the pancreas. Microscopy Research and Technique 43:313-321; (1998).
Brunicardi et al. Pancreatic polypeptide administration improves abnormal glucose metabolism in patients with chronic pancreatitis. Journal of Clinical Endocrinology and Metabolism, vol. 81, No. 10 (1996).
Reed et al. Peptide YY reduces the mortality of necrotizing pancreatitis. Abstract; Gastroenterology, vol. 112, No. 4, Suppl. pp. A476. Meeting Inf: Digestive Disease Week and the 97th Annual Meeting of the American Gastroenterological Association. Washington, DC, USA (May 11-14, 1997).
Creutzfeldt et al. Intensive medical treatment of severe actue pancreatitis. Abstract; World Journal of Surgery, vol. 5, No. 3, pp. 341-350 (1981).
Solomon et al. The glucose intolerance of acute pancreatitis; hormonal response to arginine. Abstract; Diabetes vol. 29, No. 1, pp. 22-26 (Jan. 1980).
Lochs et al., Effect of parenteral administration of fat on the glucose and fat metabolism in acute pancreatitis. Abstract; Infusionstherapie und klinische Ernahrung, vol. 9, No. 3, pp. 127-129 (Jun. 1982).
Wells, JA Additivity of Mutational Effects in Proteins. Biochemistry 29:8509-8517 (1990).
Well, JA Additivity of Mutational Effects in Proteins. Biochemistry 29:8509-8517 (1990).
Freshney, I R. Culture of Animal Cells, A Manual of Basic Technique. (Alan R. Liss, Inc. 1983, New York, NY).
Dox, I.G. et al. The Harper Collins Illustrated Medical Dictionary. (HarperCollins Publishers, Inc. 1993 New York, NY).
Ngo et al. Computational Complexity, Protein Structure Prediction and the Levinthal Paradox. The Protein Folding Problem and Tertiary Structure Prediction. 492-495 Birkhauser Boston (1994).
Chen, C., et al., “PYY and NPY: control of gastric motility via action on Y1 and Y2 receptors in the DVC”, Neurogastroenterol. Mot., 9: 109-116 (1997).
Chen, M., et al., “Sensitive Radioimmunoassay for Measurement of Circulating Peptide YY”, Gastroenterology, 87: 1332-8 (1984).
Dos Santos Medeiros, M., et al., “Processing and Metabolism of Peptide-YY: Pivotal Roles of Dipeptidylpeptidase-IV, Aminopeptidase-P, and Endopeptidase-24.11”, Endocrinology, 134: 2088-2094 (1994).
Eberlein, G., et al, “A New Molecular Form of PYY: Structural Characterization of Human PYY (3-36) and PYY (1-36)”, Peptides, 10: 797-803 (1989).
Grandt, D., et al, “Novel Generation of Hormone Receptor Specificity by Amino Terminal Processing of Peptide YY”, Biochemical and Biophysical Research Communications, 186: 3: 299-1306 (1992).
Grandt, D., et al., “Two Molecular Forms of Peptide YY (PYY) are Abundant in Human Blood: Characterization of a Radioimmunoassay Recognizing PYY 1-36 and PYY 3-36”, Regulatory Peptides, 51: 151-159 (1994).
Leibowitz, S.F., et al, “Analysis of Neuropeptide Y-Induced Feeding: Dissociation of Y(1) and Y(2) Receptor Effects on Natural Meal Patterns”, Peptides, 12: 1251-1260 (1991).
Morley, J., “An Approach to the Development of Drugs for Appetite Disorders”, Neuropsychobiology, 21: 22-30 (1989).
Morley, J., et al., “An Investigation of Tolerance to the Actions of Leptogenic and Anorexigenic Drugs in Mice”, Life Sciences, 41: 2157-2165 (1987).
Okada, S., et al, “Peripherally Not Centrally Administered Peptide YY (PYY) Decreases High Fat Diet Intake”, Endocrinology, Abstract 520B (1993).
Tatemoto, K., et al, “Isolation and Primary Structure of Human Peptide YY”, Biochemical and Biophysical Research Communication 157:2: 713-717 (1988).
Adrian, T.E., et al., “Human Distribution and Release of a Putative New Gut Hormone, Peptide YY,” Gastroenterology, 89:1070-7 (1985).
Allen, J.M., et al., “Effects of Peptide YY and Neuropeptide Y on Gastric Emptying in Man,” Digestion, 30:255-262 (1984).
Asakawa, A., et al., “Mouse pancreatic polypeptide modulates food intake, while not influencing anxiety in mice,” Peptides, 20:1445-1448 (1999).
Balasubramaniam, A., et al., “Structure-Activity Studies Including a (psi)(CH2-NH) Scan of Peptide YY (PYY) Active Site, PYY(22-36), for Interaction with Rat Intestinal PYY Receptors: Development of Analogues with Potent in Vivo Activity in the Intestine,” J. Med. Chem., 43:3420-3427 (2000).
Hoentjen, F., et al., “Role of Circulating Peptide YY in the Inhibition of Gastric Acid Secretion by Dietary Fat in Humans,” Scand J Gastroenterol, 35:166-171 (2000).
Iyengar, S., et al., “Characterization of Neuropeptide Y-Induced Feeding in Mice: Do Y1-Y6 Receptor Subtypes Mediate F

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods and reagents for treating glucose metabolic disorders does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and reagents for treating glucose metabolic disorders, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and reagents for treating glucose metabolic disorders will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4226342

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.