Bleaching and dyeing; fluid treatment and chemical modification – Dye or potential dye composition – additive – treatment,... – Polymeric dye – e.g. – a chromophore pendant from an addition...
Patent
1989-09-14
1991-10-01
Lieberman, Paul
Bleaching and dyeing; fluid treatment and chemical modification
Dye or potential dye composition, additive, treatment,...
Polymeric dye, e.g., a chromophore pendant from an addition...
8554, 8648, 8517, C09D 6910
Patent
active
050530542
ABSTRACT:
Reagents and methods for intracellular staining of anionic materials as provided. The inherent staining characteristics of a fluorescent molecule may be suitably altered by covalently linking a plurality of said molecules to a nonimmunoglobulin derived cationic polymer having the desired staining specificity. By careful selection of the net charge and size of the dye polymer complex, diffusion through the cellular membrane can be enhanced and an enhanced fluorescent signal obtained by localization of a plurality of fluorescent molecules at the site of interest.
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Pierce, 1989 Handbook and General Catalog, pp. 209-312.
Azad A. R. M.
Kirchanski Stefan J.
Natale Peter J.
Lieberman Paul
Matthews Gale F.
Ortho Pharmaceutical Corporation
Swope Bradley A.
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