Methods and reagents for regulating telomere length and telomera

Details Methods and reagents for regulating telomere length and telomera Methods and reagents for regulating telomere length and telomera

1996-09-13

1999-01-12

Wax, Robert A.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

536 232, 536 2431, 4352523, 4353201, 435 691, 435 913, 435194, 43525411, 530350, C12N 120, C12N 912, C07H 2104, C07K 100

Patent

active

058587772

ABSTRACT:
Purified and recombinant proteins TPC2 and TPC3 and recombinant or synthetic oligonucleotides corresponding to those proteins or fragments thereof can be used to detect regulators of telomere length and telomerase activity in mammalian cells and for a variety of related diagnostic and therapeutic purposes.

REFERENCES:
patent: 5583016 (1996-12-01), Villeponteau et al.
Hillier et al. Genebank. Accession No. R19233, Apr. 14, 1995.
Dunnen et al. Gene 78:201-213, 1989.
Counter et al. PNAS 91:2900-2904, 1994.
Accession No: X75014. See result 9 of the enclosed sequence search, Aug. 12, 1994.
Accession No. F13486. See result 5 of the enclosed sequence search, Mar. 5, 1995.

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