Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1984-02-24
1986-02-11
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435190, 435911, C12P 1902, C12N 904, C12R 1645
Patent
active
045699100
ABSTRACT:
Methods for producing substantially pure pyranosone from pyranose, especially glucosone from glucose. A pyranose-2-oxidase enzyme which is free of substantially all glucosone-utilizing enzyme contaminants which are measurably active at a selected pH between about 4.4 and 7.0 is reacted in solution with a pyranose and oxygen to produce the corresponding pyranosone. Hydrogen peroxide co-produced in the reaction is maintained at a concentration below about 10.sup.-3 M, by substantially pure catalase. The reaction is carried out at the selected pH. The methods and reagents are also applicable to producing xylosone from xylose, 5-ketofructose from sorbose, and mixtures of 2-ketogluconic and isoascorbic acid from delta-gluconolactone.
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Fernandes Peter M.
Halenbeck Robert F.
Koths Kirston E.
Cetus Corporation
Ciotti Thomas E.
Fineman Elliott L.
Halluin Albert P.
Shapiro Lionel M.
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